Tetrahydroxypteridine cycloisomerase

In enzymology, a tetrahydroxypteridine cycloisomerase (EC 5.5.1.3) is an enzyme that catalyzes the chemical reaction

tetrahydroxypteridine xanthine-8-carboxylate
tetrahydroxypteridine cycloisomerase
Identifiers
EC number5.5.1.3
CAS number37318-54-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Hence, this enzyme has one substrate, tetrahydroxypteridine, and one product, xanthine-8-carboxylate.

This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is tetrahydroxypteridine lyase (isomerizing). It employs one cofactor, NAD+.

References

    • Mcnutt WS, Damle SP (December 1964). "Tetraoxypteridine isomerase". The Journal of Biological Chemistry. 239: 4272–9. PMID 14247682.


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