Pwo DNA polymerase

Pwo polymerase is a thermostable DNA polymerase used for the polymerase chain reaction. The abbreviation stands for Pyrococcus woesei, a thermophilic archaeon, from which this polymerase was isolated. This polymerase breaks when reaching erroneous uracil in DNA from the chain extension and, through this readahead function, fewer defective DNA clones are synthesized. It is used much less than the usual Taq or Pfu polymerases.[1]

See also: Taq polymerase, Pfu DNA polymerase, Vent DNA polymerase, and Variants of PCR
DNA polymerase
Identifiers
OrganismPyrococcus woesei
Symbolpol
UniProtP61876

References
  1. Ghasemi A, Salmanian AH, Sadeghifard N, Salarian AA, Gholi MK (September 2011). "Cloning, expression and purification of Pwo polymerase from Pyrococcus woesei". Iranian Journal of Microbiology. 3 (3): 118–22. PMC 3279813. PMID 22347593.
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