Phosphatidylinositol a-mannosyltransferase

In enzymology, a phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) is an enzyme that catalyzes the chemical reaction in which at least one alpha-D-mannose residues are transferred from GDP-mannose to positions 6, 2 and others in 1-phosphatidyl-myo-inositol.

phosphatidylinositol alpha-mannosyltransferase
Identifiers
EC number2.4.1.57
CAS number37277-65-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase. Other names in common use include GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase, GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase, guanosine diphosphomannose-phosphatidyl-inositol, alpha-mannosyltransferase, and phosphatidyl-myo-inositol alpha-mannosyltransferase.

References

    • Brennan P, Ballou CE (1968). "Phosphatidylmyoinositol monomannoside in Propionibacterium shermanii". Biochem. Biophys. Res. Commun. 30 (1): 69–75. doi:10.1016/0006-291X(68)90714-6. PMID 4295288.


    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.