N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase

N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase (EC 2.4.1.141, UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase, uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase, N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase.[1][2] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol UDP + N,N'-diacetylchitobiosyl-diphosphodolichol
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
Identifiers
EC number2.4.1.141
CAS number75536-54-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

References
  1. Sharma CB, Lehle L, Tanner W (August 1982). "Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast". European Journal of Biochemistry. 126 (2): 319–25. doi:10.1111/j.1432-1033.1982.tb06781.x. PMID 6215245.
  2. Turco SJ, Heath EC (May 1977). "Glucuronosyl-N-acetylglucosaminyl pyrophosphoryldolichol. Formation in SV40-transformed human lung fibroblasts and biosynthesis in rat lung microsomal preparations". The Journal of Biological Chemistry. 252 (9): 2918–28. PMID 192724.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.