Meso-tartrate dehydrogenase

In enzymology, a meso-tartrate dehydrogenase (EC 1.3.1.7) is an enzyme that catalyzes the chemical reaction

meso-tartrate + NAD+ dihydroxyfumarate + NADH + H+
meso-tartrate dehydrogenase
Identifiers
EC number1.3.1.7
CAS number37251-06-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are meso-tartaric acid and NAD+, whereas its 3 products are dihydroxyfumarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-tartrate:NAD+ oxidoreductase. This enzyme participates in glyoxylic acid and dicarboxylic acid metabolism.

References

    • Kohn LD, Jakoby WB (1966). "L- and mesotartaric acid dehydrogenase (crystalline)". Carbohydrate Metabolism. Methods in Enzymology. 9. pp. 236–240. doi:10.1016/0076-6879(66)09055-4. ISBN 978-0-12-181809-8.


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