JWH-057
JWH-057, also known as deoxy-Δ8-THC-DMH, is a selective cannabinoid ligand, with a binding affinity of Ki = 2.9 ± 1.6 nM for the CB2 subtype, and Ki = 23 ± 7 nM for CB1.[1]
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C25H38O |
| Molar mass | 354.578 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
References
- Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH (1996). "Synthesis and Pharmacology of a Very Potent Cannabinoid Lacking a Phenolic Hydroxyl with High Affinity for the CB2 Receptor". J. Med. Chem. 39 (20): 3875–3877. doi:10.1021/JM960394Y. PMID 8831752.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.