AM-087
AM-087 (part of the AM cannabinoid series) is an analgesic drug which acts as a cannabinoid agonist.[1] It is a derivative of Δ8-THC, substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43 nM, making it around 100 times more potent than THC itself. This is most likely due to the bulky bromine substituent on the side chain.[2]
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| Formula | C23H33BrO2 |
| Molar mass | 421.419 g·mol−1 |
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See also
References
- Martin BR, Compton DR, Semus SF, Lin S, Marciniak G, Grzybowska J, et al. (October 1993). "Pharmacological evaluation of iodo and nitro analogs of Δ8-THC and Δ9-THC". Pharmacology, Biochemistry, and Behavior. 46 (2): 295–301. doi:10.1016/0091-3057(93)90356-X. PMID 8265683.
- Charalambous A, Lin S, Marciniak G, Banijamali A, Friend FL, Compton DR, et al. (November 1991). "Pharmacological evaluation of halogenated delta 8-THC analogs". Pharmacology, Biochemistry, and Behavior. 40 (3): 509–12. doi:10.1016/0091-3057(91)90355-6. PMID 1666915.
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