Isoflupredone

Isoflupredone, also known as deltafludrocortisone and 9α-fluoroprednisolone, is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2]

Isoflupredone
Clinical data
Other names9α-Fluoroprednisolone; Fluoroprednisolone; Deltafludrocortisone; δ-Fludrocortisone; δ-Fluorocortisone; 1-Dehydro-9α-fluorohydrocortisone; 9α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.005.839
Chemical and physical data
FormulaC21H27FO5
Molar mass378.440 g·mol−1
3D model (JSmol)

Its acetate ester, isoflupredone acetate, is used in veterinary medicine.[3]

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 707–. ISBN 978-1-4757-2085-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 573–. ISBN 978-3-88763-075-1.
  3. "Predef 2X Sterile Aqueous Suspension". drugs.com.

Further reading

  • Montoliu J, Botey A, Trilla A, Revert L (November 1984). "Pseudoprimary aldosteronism from the topical application of 9-alpha-fluorprednisolone to the skin". Clinical Nephrology. 22 (5): 262–6. PMID 6394185.
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