Hydrogenase (acceptor)

In enzymology, a hydrogenase (acceptor) (EC 1.12.99.6) is an enzyme that catalyzes the chemical reaction

H2 + A AH2
Hydrogenase (acceptor)
Identifiers
EC number1.12.99.6
CAS number9027-05-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Thus, the two substrates of this enzyme are H2 and A, whereas its product is AH2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other acceptors. The systematic name of this enzyme class is hydrogen:acceptor oxidoreductase. Other names in common use include H2 producing hydrogenase[ambiguous], hydrogen-lyase[ambiguous], hydrogenlyase[ambiguous], uptake hydrogenase[ambiguous], and hydrogen:(acceptor) oxidoreductase.

References

    • Shug AL, Wilson PW, Green DE, Mahler HR (1954). "The role of molybdenum and flavin in hydrogenase". J. Am. Chem. Soc. 76 (12): 3355–3356. doi:10.1021/ja01641a090.
    • Adams MW, Mortenson LE, Chen J-S (1981). "Hydrogenase". Biochim. Biophys. Acta. 594: 105–176. doi:10.1016/0304-4173(80)90007-5.
    • Vignais PM, Billoud B, Meyer J (2001). "Classification and phylogeny of hydrogenases". FEMS Microbiol. Rev. 25 (4): 455–501. doi:10.1111/j.1574-6976.2001.tb00587.x. PMID 11524134.


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