Glucose-1-phosphate phosphodismutase
In enzymology, a glucose-1-phosphate phosphodismutase (EC 2.7.1.41) is an enzyme that catalyzes the chemical reaction
- 2 D-glucose 1-phosphate ⇌ D-glucose + D-glucose 1,6-bisphosphate
| glucose-1-phosphate phosphodismutase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.41 | ||||||||
| CAS number | 9026-25-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, D-glucose 1-phosphate, and two products, D-glucose and D-glucose 1,6-bisphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase. This enzyme participates in glycolysis / gluconeogenesis and starch and sucrose metabolism.
References
- LELOIR LF, TRUCCO RE, et al. (1949). "The formation of glucose diphosphate by Escherichia coli". Arch. Biochem. 24 (1): 65–74. PMID 15400363.
- Sidbury JB, Rosenberg LL, Najjar VA (1956). "Muscle glucose-1-phosphate transphosphorylase". J. Biol. Chem. 222 (1): 89–96. PMID 13366982.
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