Diphosphate—glycerol phosphotransferase
In enzymology, a diphosphate-glycerol phosphotransferase (EC 2.7.1.79) is an enzyme that catalyzes the chemical reaction
- diphosphate + glycerol phosphate + glycerol 1-phosphate
| diphosphate-glycerol phosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.79 | ||||||||
| CAS number | 37278-13-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are diphosphate and glycerol, whereas its two products are phosphate and glycerol 1-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is diphosphate:glycerol 1-phosphotransferase. Other names in common use include PPi-glycerol phosphotransferase, and pyrophosphate-glycerol phosphotransferase.
References
- Stetten MR (June 1970). "Enzymatic synthesis of glycerol I-phosphate. Elevation in diabetic and fasted animals, compared with glucose-6-phosphatase and related enzyme activities". Biochimica et Biophysica Acta (BBA) - General Subjects. 208 (3): 394–403. doi:10.1016/0304-4165(70)90212-6. PMID 4319153.
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