Dextransucrase
In enzymology, a dextransucrase (EC 2.4.1.5) is an enzyme that catalyzes the chemical reaction
- sucrose + (1,6-alpha-D-glucosyl)n D-fructose + (1,6-alpha-D-glucosyl)n+1
| dextransucrase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.5 | ||||||||
| CAS number | 9032-14-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are sucrose and (1,6-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,6-alpha-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase. Other names in common use include sucrose 6-glucosyltransferase, SGE, CEP, and sucrose-1,6-alpha-glucan glucosyltransferase. This enzyme participates in starch and sucrose metabolism and two-component system - general.
References
- BAILEY RW (1959). "Transglucosidase activity of rumen strains of Streptococcus bovis 2. Isolation and properties of dextransucrase". Biochem. J. 72 (1): 42–9. PMC 1196878. PMID 13651133.
- Bailey RW, Barker SA, Bourne EJ, Stacey M. "Immunopolysaccharides. Part VI. The isolation and properties of the dextransucrase of Betacoccus arabinosaceous". J. Chem. Lond. Soc.: 3530–3536. doi:10.1039/jr9570003530.
- Hehre EJ (1951). "Enzymic synthesis of polysaccharides: a biological type of polymerization". Adv. Enzymol. Relat. Subj. Biochem. Advances in Enzymology - and Related Areas of Molecular Biology. 11: 297–337. doi:10.1002/9780470122563.ch6. ISBN 9780470122563.
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