Cycloisomaltooligosaccharide glucanotransferase

Cycloisomaltooligosaccharide glucanotransferase (EC 2.4.1.248) is an enzyme with systematic name (1->6)-alpha-D-glucan:(1->6)-alpha-D-glucan 6-alpha-D-(1->6alpha-D-glucano)-transferase (cyclizing).[1][2][3] This enzyme catalyses the following chemical reaction

cyclizes part of a (1->6)-alpha-D-glucan chain by formation of a (1->6)-alpha-D-glucosidic bond
Cycloisomaltooligosaccharide glucanotransferase
Identifiers
EC number2.4.1.248
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is specific for (1->6)-alpha-D-glucans (dextrans).

References

  1. Oguma T, Horiuchi T, Kobayashi M (1993). "Novel Cyclic dextrins, Cycloisomaltooligosaccharides, from Bacillus sp. T-3040 culture". Biosci. Biotechnol. Biochem. 57: 1225–1227. doi:10.1271/bbb.57.1225. PMID 27281012.
  2. Oguma, T.; Tobe, K. & Kobayashi, M. (1994). "Purification and properties of a novel enzyme from Bacillus spp. T-3040, which catalyzes the conversion of dextran to cyclic isomaltooligosaccharides". FEBS Lett. 345: 135–138. doi:10.1016/0014-5793(94)00418-8. PMID 7515357.
  3. Yamamoto, T.; Terasawa, K.; Kim, Y.M.; Kimura, A.; Kitamura, Y.; Kobayashi, M. & Funane, K. (2006). "Identification of catalytic amino acids of cyclodextran glucanotransferase from Bacillus circulans T-3040". Biosci. Biotechnol. Biochem. 70: 1947–1953. doi:10.1271/bbb.60105. PMID 16926507.
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