Chalcone 4'-O-glucosyltransferase

Chalcone 4'-O-glucosyltransferase (EC 2.4.1.286, 4'CGT) is an enzyme with systematic name UDP-alpha-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucosyltransferase.[1] This enzyme catalyses the following chemical reaction

(1) UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
(2) UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone UDP + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside
Chalcone 4'-O-glucosyltransferase
Identifiers
EC number2.4.1.286
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from the plant Antirrhinum majus (snapdragon).

References

  1. Ono E, Fukuchi-Mizutani M, Nakamura N, Fukui Y, Yonekura-Sakakibara K, Yamaguchi M, Nakayama T, Tanaka T, Kusumi T, Tanaka Y (July 2006). "Yellow flowers generated by expression of the aurone biosynthetic pathway". Proceedings of the National Academy of Sciences of the United States of America. 103 (29): 11075–80. Bibcode:2006PNAS..10311075O. doi:10.1073/pnas.0604246103. PMC 1544175. PMID 16832053.
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