4-hydroxybenzoate 4-O-beta-D-glucosyltransferase

In enzymology, a 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase (EC 2.4.1.194) is an enzyme that catalyzes the chemical reaction

UDP-glucose + 4-hydroxybenzoate UDP + 4-(beta-D-glucosyloxy)benzoate
4-hydroxybenzoate 4-O-beta-D-glucosyltransferase
Identifiers
EC number2.4.1.194
CAS number120860-68-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are UDP-glucose and 4-hydroxybenzoate, whereas its two products are UDP and 4-(beta-D-glucosyloxy)benzoate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase, UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid, glucosyltransferase, HBA glucosyltransferase, p-hydroxybenzoate glucosyltransferase, PHB glucosyltransferase, and PHB-O-glucosyltransferase.

References

    • Katsumata T, Shige H, Ejiri SI (1989). "Biochemical-studies on pollen. 34. UDP glucose-4-(beta-D-glucopyranosyloxy) benzoic-acid glucosyltransferase from the pollen of Pinus densiflora". Phytochemistry. 28 (2): 359–362. doi:10.1016/0031-9422(89)80013-5.


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