1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16, N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5-phosphoribosyl)-4-imidazolecarboxamide isomerase, phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase, N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase) is an enzyme with systematic name 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide aldose-ketose-isomerase.[1] This enzyme catalyses the following chemical reaction
- 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide
| 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 HisAp hexamer, Arthrobacter aurescens | |||||||||
| Identifiers | |||||||||
| EC number | 5.3.1.16 | ||||||||
| CAS number | 37318-43-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
References
- Margolies MN, Goldberger RF (July 1966). "Isolation of the fourth (isomerase) of histidine biosynthesis from Salmonella typhimurium". The Journal of Biological Chemistry. 241 (14): 3262–9. PMID 5330429.
External links
- 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide+isomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
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