ZMYM2

ZMYM2
Identifiers
AliasesZMYM2, FIM, MYM, RAMP, SCLL, ZNF198, zinc finger MYM-type containing 2
External IDsMGI: 1923257 HomoloGene: 12631 GeneCards: ZMYM2
Gene location (Human)
Chr.Chromosome 13 (human)[1]
Band13q12.11Start19,958,670 bp[1]
End20,091,829 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

7750

76007

Ensembl

ENSG00000121741

ENSMUSG00000021945

UniProt

Q9UBW7

Q9CU65

RefSeq (mRNA)

NM_029498
NM_177627
NM_001360643

RefSeq (protein)

NP_083774
NP_001347572
NP_808295

Location (UCSC)Chr 13: 19.96 – 20.09 MbChr 14: 56.89 – 56.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger MYM-type protein 2 is a protein that in humans is encoded by the ZMYM2 gene.[5][6][7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000121741 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021945 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Smedley D, Hamoudi R, Clark J, Warren W, Abdul-Rauf M, Somers G, Venter D, Fagan K, Cooper C, Shipley J (April 1998). "The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP". Human Molecular Genetics. 7 (4): 637–42. doi:10.1093/hmg/7.4.637. PMID 9499416.
  6. ↑ Xiao S, Nalabolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, Stone R, Weissman SM, Hudson TJ, Fletcher JA (January 1998). "FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome". Nature Genetics. 18 (1): 84–7. doi:10.1038/ng0198-84. PMID 9425908.
  7. ↑ "Entrez Gene: ZMYM2 zinc finger, MYM-type 2".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Popovici C, Adélaïde J, Ollendorff V, Chaffanet M, Guasch G, Jacrot M, Leroux D, Birnbaum D, Pébusque MJ (May 1998). "Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)". Proceedings of the National Academy of Sciences of the United States of America. 95 (10): 5712–7. doi:10.1073/pnas.95.10.5712. PMC 20444. PMID 9576949.
  • Still IH, Cowell JK (August 1998). "The t(8;13) atypical myeloproliferative disorder: further analysis of the ZNF198 gene and lack of evidence for multiple genes disrupted on chromosome 13". Blood. 92 (4): 1456–8. PMID 9694738.
  • Reiter A, Sohal J, Kulkarni S, Chase A, Macdonald DH, Aguiar RC, Gonçalves C, Hernandez JM, Jennings BA, Goldman JM, Cross NC (September 1998). "Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome". Blood. 92 (5): 1735–42. PMID 9716603.
  • Kulkarni S, Reiter A, Smedley D, Goldman JM, Cross NC (January 1999). "The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome". Genomics. 55 (1): 118–21. doi:10.1006/geno.1998.5634. PMID 9889006.
  • Ollendorff V, Guasch G, Isnardon D, Galindo R, Birnbaum D, Pébusque MJ (September 1999). "Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation". The Journal of Biological Chemistry. 274 (38): 26922–30. doi:10.1074/jbc.274.38.26922. PMID 10480903.
  • Matsumoto K, Morita K, Takada S, Sakura T, Shiozaki H, Murakami H, Miyawaki S (December 1999). "A chronic myelogenous leukemia-like myeloproliferative disorder accompanied by T-cell lymphoblastic lymphoma with chromosome translocation t(8;13)(p11;q12): a Japanese case". International Journal of Hematology. 70 (4): 278–82. PMID 10643154.
  • Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R (February 2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". The Journal of Biological Chemistry. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763.
  • Baumann H, Kunapuli P, Tracy E, Cowell JK (May 2003). "The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors". The Journal of Biological Chemistry. 278 (18): 16198–208. doi:10.1074/jbc.M300018200. PMID 12594223.
  • Kunapuli P, Somerville R, Still IH, Cowell JK (May 2003). "ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins". Oncogene. 22 (22): 3417–23. doi:10.1038/sj.onc.1206408. PMID 12776193.
  • Warner DR, Roberts EA, Greene RM, Pisano MM (December 2003). "Identification of novel Smad binding proteins". Biochemical and Biophysical Research Communications. 312 (4): 1185–90. doi:10.1016/j.bbrc.2003.11.049. PMID 14651998.
  • Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (July 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.


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