TFEC

TFEC
Identifiers
AliasesTFEC, TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L, transcription factor EC
External IDsMGI: 1333760 HomoloGene: 32148 GeneCards: TFEC
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q31.2Start115,935,148 bp[1]
End116,159,896 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

22797

21426

Ensembl

ENSG00000105967

ENSMUSG00000029553

UniProt

O14948

Q9WTW4

RefSeq (mRNA)

NM_001018058
NM_001244583
NM_012252

NM_031198

RefSeq (protein)

NP_001018068
NP_001231512
NP_036384

NP_112475

Location (UCSC)Chr 7: 115.94 – 116.16 MbChr 6: 16.83 – 16.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription factor EC is a protein that in humans is encoded by the TFEC gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000105967 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029553 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Yasumoto K, Shibahara S (Aug 1997). "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator". Biochim Biophys Acta. 1353 (1): 23–31. doi:10.1016/s0167-4781(97)00034-1. PMID 9256061.
  6. ↑ "Entrez Gene: TFEC transcription factor EC".

Further reading

  • Zhao GQ, Zhao Q, Zhou X, et al. (1993). "TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation". Mol. Cell. Biol. 13 (8): 4505–12. PMC 360062. PMID 8336698.
  • Steingrímsson E, Tessarollo L, Reid SW, et al. (1999). "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization". Development. 125 (23): 4607–16. PMID 9806910.
  • Chung MC, Kim HK, Kawamoto S (2001). "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells". Biochemistry. 40 (30): 8887–97. doi:10.1021/bi002847d. PMID 11467950.
  • Mansky KC, Sulzbacher S, Purdom G, et al. (2002). "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter". J. Leukoc. Biol. 71 (2): 304–10. PMID 11818452.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.


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