Streptogrisin B

Streptogrisin B
Identifiers
EC number 3.4.21.81
CAS number 55071-87-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Streptogrisin B (EC 3.4.21.81, Streptomyces griseus protease B, pronase B, serine proteinase B, Streptomyces griseus proteinase B, Streptomyces griseus proteinase 1, Streptomyces griseus serine proteinase B) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with trypsin-like specificity

This enzyme is isolated from Streptomyces griseus.

References

  1. Jurasek L, Fackre D, Smillie LB (September 1969). "Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus". Biochemical and Biophysical Research Communications. 37 (1): 99–105. doi:10.1016/0006-291x(69)90885-7. PMID 4899581.
  2. Fujinaga M, Read RJ, Sielecki A, Ardelt W, Laskowski M, James MN (August 1982). "Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey". Proceedings of the National Academy of Sciences of the United States of America. 79 (16): 4868–72. doi:10.1073/pnas.79.16.4868. PMC 346786. PMID 6750612.
  3. Read RJ, Fujinaga M, Sielecki AR, James MN (September 1983). "Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution". Biochemistry. 22 (19): 4420–33. doi:10.1021/bi00288a012. PMID 6414511.
  4. Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT (August 1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". Journal of Bacteriology. 169 (8): 3778–84. PMC 212465. PMID 3112129.
  5. Greenblatt HM, Ryan CA, James MN (January 1989). "Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution". Journal of Molecular Biology. 205 (1): 201–28. doi:10.1016/0022-2836(89)90376-8. PMID 2494344.
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