Polyamine oxidase (propane-1,3-diamine-forming)

Polyamine oxidase (propane-1,3-diamine-forming)
Identifiers
EC number 1.5.3.14
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Polyamine oxidase (propane-1,3-diamine-forming) (EC 1.5.3.14, MPAO, maize PAO) is an enzyme with systematic name spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming).[1][2] This enzyme catalyses the following chemical reaction

spermidine + O2 + H2O propane-1,3-diamine + 4-aminobutanal + H2O2

The products of the reaction cannot be converted directly to other polyamines.

References

  1. Tavladoraki, P.; Schinina, M.E.; Cecconi, F.; Di Agostino, S.; Manera, F.; Rea, G.; Mariottini, P.; Federico, R.; Angelini, R. (1998). "Maize polyamine oxidase: primary structure from protein and cDNA sequencing". FEBS Lett. 426: 62–66. doi:10.1016/S0014-5793(98)00311-1. PMID 9598979.
  2. Federico, R.; Ercolini, L.; Laurenzi, M.; Angelini, R. (1996). "Oxidation of acetylpolyamines by maize polyamine oxidase". Phytochemistry. 43: 339–341. doi:10.1016/0031-9422(96)00316-0.
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