O-phosphoseryl-tRNASec kinase
| O-phosphoseryl-tRNASec kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.164 | ||||||||
| CAS number | 91273-83-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
O-phosphoseryl-tRNASec kinase (EC 2.7.1.164, PSTK, phosphoseryl-tRNA[Ser]Sec kinase, phosphoseryl-tRNASec kinase) is an enzyme with systematic name ATP:L-seryl-tRNASec O-phosphotransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + L-seryl-tRNASec ADP + O-phospho-L-seryl-tRNASec
In archaea and eukarya selenocysteine formation is achieved by a two-step process.
References
- ↑ Carlson, B.A.; Xu, X.M.; Kryukov, G.V.; Rao, M.; Berry, M.J.; Gladyshev, V.N.; Hatfield, D.L. (2004). "Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase". Proc. Natl. Acad. Sci. USA. 101 (35): 12848–12853. doi:10.1073/pnas.0402636101. PMC 516484. PMID 15317934.
- ↑ Sherrer, R.L.; O'Donoghue, P.; Soll, D. (2008). "Characterization and evolutionary history of an archaeal kinase involved in selenocysteinyl-tRNA formation". Nucleic Acids Res. 36: 1247–1259. doi:10.1093/nar/gkm1134. PMC 2275090. PMID 18174226.
- ↑ Khangulov, S.V.; Gladyshev, V.N.; Dismukes, G.C.; Stadtman, T.C. (1998). "Selenium-containing formate dehydrogenase H from Escherichia coli: a molybdopterin enzyme that catalyzes formate oxidation without oxygen transfer". Biochemistry. 37: 3518–3528. doi:10.1021/bi972177k. PMID 9521673.
External links
- O-phosphoseryl-tRNASec+kinase at the US National Library of Medicine Medical Subject Headings (MeSH)
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