Nihar Ranjan Jana

Nihar Ranjan Jana
Born 1965
India
Residence Gurgaon, Haryana, India
Nationality Indian
Alma mater
Known for Studies on E3 ubiquitin ligases
Awards
Scientific career
Fields
Institutions

Nihar Ranjan Jana (born 1965) is an Indian neuroscientist and a professor at the National Brain Research Centre. Known for his studies on E3 ubiquitin ligases, Jana is an elected fellow of the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2008.

Biography

National Brain Research Centre.

Nihar Ranjan Jana, born in 1965,[1] did his doctoral studies at the Visva-Bharati University and after securing a PhD in 1996, he completed his post-doctoral work at RIKEN Brain Science Institute, Japan.[2] On his return to India, he joined the National Brain Research Centre (NBRC) as a scientist and faculty member in 2001. He served as an associate professor at NBRC[3] before becoming a professor and holds the position of a Grade IV scientist.[4] He hosts a number of research scholars at his laboratory at NBRC[5] and also serves as a visiting faculty at the School of Studies in of Neuroscience of the Jiwaji University.[6]

Jana resides in Gurgaon, in Haryana.[1]

Legacy

Neem tree seeds

Jana is involved in the research on neurological disorders caused by proteopathy and has carried out investigations on the role of E3 ubiquitin ligases as a causative factor.[4] He has demonstrated how the ligases control cellular protein quality and how the absence of such an activity caused neuronal dysfunction or neurodegeneration. He led a team of scientists from NBRC and Bose Institute who conducted experiments on Huntington's disease, an inherited neurological disorder which led to the death of brain cells, and suggested azadiradione, a compound found in the seeds of Azadirachta indica (commonly known as neem) as a possible therapeutic molecule.[7] He has also identified new targets in diseases such as Lafora disease, a form of epilepsy, autism and Angelman syndrome which has reportedly widened the understanding of their pathogenesis.[2] His studies have been documented by way of a number of articles[8][note 1] and ResearchGate, an online repository of scientific articles has listed 94 of them.[9]

Jana is a member of the Neurobiology Task force of the Department of Biotechnology.[3] He has delivered keynote or invited speeches at seminars such as the International Conference on Neurodegenerative Diseases: Pathogenesis to Therapy - 2015 held at the Indian Institute of Science, Bengaluru[10] and the IAN 2017 of the Indian Academy of Neurosciences held at Ravenshaw University, Cuttack.[11]

Awards and honors

The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2008[12] and the National Academy of Sciences, India elected him as a fellow the same year.[13] He is also an elected fellow of the West Bengal Academy of Science and Technology and in 2012, he received the VASVIK Industrial Research Award for what the award citation mentioned as pioneering work on Huntington's disease.[14] The award orations delivered by him include the 2013 edition of the K. T. Shetty Memorial Oration of the Indian Academy of Neurosciences.[2]

Selected bibliography

  • Singh, Brijesh Kumar; Vatsa, Naman; Nelson, Vinod K.; Kumar, Vipendra; Kumar, Shashi Shekhar; Mandal, Subhash C.; Pal, Mahadeb; Jana, Nihar Ranjan (2018-01-02). "Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease". Molecular Neurobiology: 1–10. doi:10.1007/s12035-017-0853-3. ISSN 0893-7648.
  • Singh, Brijesh Kumar; Vatsa, Naman; Kumar, Vipendra; Shekhar, Shashi; Sharma, Ankit; Jana, Nihar Ranjan. "Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer's disease" (PDF). Canadian Journal of Biotechnology. 1 (Special Issue): 177–177. doi:10.24870/cjb.2017-a163.
  • Singh, Brijesh Kumar; Vatsa, Naman; Kumar, Vipendra; Shekhar, Shashi; Sharma, Ankit; Jana, Nihar Ranjan (2017-10-15). "Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer's disease". Human Molecular Genetics. 26 (20): 4042–4054. doi:10.1093/hmg/ddx295. ISSN 0964-6906.

See also

Notes

  1. ↑ Please see Selected bibliography section

References

  1. 1 2 "NASI fellows". National Academy of Sciences, India. 2017-12-21. Retrieved 2017-12-21.
  2. 1 2 3 "Prof. Nihar R Jana, National Brain Research Centre, awarded the KT Shetty Memorial Oration" (PDF). Indian Academy of Neurosciences. Retrieved 2018-01-08.
  3. 1 2 "Dr. Nihar Ranjan Jana - DBT Neurobiology Task force". dbt-neuro.ncbs.res.in. 2018-01-08. Retrieved 2018-01-08.
  4. 1 2 "Professor NBRC". National Brain Research Centre. 2018-01-08. Retrieved 2018-01-08.
  5. ↑ "Lab members". National Brain Research Centre. 2018-01-08. Retrieved 2018-01-08.
  6. ↑ "School of Studies in Neuroscience, Jiwaji University, Gwalior". www.neuroscienceju.com. 2018-01-09. Retrieved 2018-01-09.
  7. ↑ "Neem hope in brain disorder treatment". The Telegraph. 7 January 2018. Retrieved 2018-01-09.
  8. ↑ "On Google Scholar". Google Scholar. 2018-01-08. Retrieved 2018-01-08.
  9. ↑ "On ResearchGate". On ResearchGate. 2018-01-08. Retrieved 2018-01-08.
  10. ↑ "Centre for Brain Research, IISc Bangalore, India". www.cbr.iisc.ac.in. 2018-01-09. Retrieved 2018-01-09.
  11. ↑ "IAN 2017, Ravenshaw University, Cuttack, Odisha, India". IAN 2017, Ravenshaw University, Cuttack, Odisha, India. Retrieved 2018-01-09.
  12. ↑ "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Retrieved 2017-11-20.
  13. ↑ "NASI Year Book 2015" (PDF). National Academy of Sciences, India. 2017-12-17. Retrieved 2017-12-17.
  14. ↑ "VASVIK Industrial Research Award". www.vasvik.org. 2018-01-09. Retrieved 2018-01-09.
  • "Publications Authored by Nihar Ranjan Jana - PubFacts.com". www.pubfacts.com. 2018-01-08. Retrieved 2018-01-08.
  • "Speakers - International Symposium on Neurodegenerative Disorders 2017". www.isnd2017.com. 2018-01-09. Retrieved 2018-01-09.
  • "World Neuro Congress 2017". World Neuro Congress 2017. 2018-01-09. Retrieved 2018-01-09.
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