NP-40

NP-40 is a commercially available detergent with CAS 9016-45-9. The full name of NP-40 is Tergitol-type NP-40, which is nonyl phenoxypolyethoxylethanol.[1]

Care should be taken to avoid confusing NP-40 with Nonidet P-40 (octyl phenoxypolyethoxylethanol). Its HLB value is 12.9 [2] compared to 13.4 for IGEPAL CA-630. NP-40 is often used to break open all membranes within a cell, including the nuclear membrane. To break only the cytoplasmic membrane, other detergents such as IGEPAL CA-630 (Nonidet P-40) can be used. NP-40 is an ethoxylated nonylphenol for non-ionic surfactants and can act as emulsifier and demulsifier agent.

NP-40 has applications in paper & textile processing, paints & coatings, and agrochemical manufacturing.

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