NLRP9

NLRP9
Identifiers
AliasesNLRP9, CLR19.1, NALP9, NOD6, PAN12, NLR family, pyrin domain containing 9, NLR family pyrin domain containing 9
External IDsOMIM: 609663 MGI: 2675377 HomoloGene: 18530 GeneCards: NLRP9
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.42Start55,708,432 bp[1]
End55,738,402 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

338321

243874

Ensembl

ENSG00000185792

ENSMUSG00000060508

UniProt

Q7RTR0

Q66X22

RefSeq (mRNA)

NM_176820

NM_194058

RefSeq (protein)

NP_789790

NP_918947

Location (UCSC)Chr 19: 55.71 – 55.74 MbChr 7: 19.99 – 20.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes.[5][6][7] It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185792 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060508 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Dalbiès-Tran R, Papillier P, Pennetier S, Uzbekova S, Monget P (August 2005). "Bovine mater-like NALP9 is an oocyte marker gene". Mol. Reprod. Dev. 71 (4): 414–21. doi:10.1002/mrd.20298. PMID 15892040.
  6. ↑ Ponsuksili S, Brunner RM, Goldammer T, et al. (March 2006). "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. doi:10.1095/biolreprod.105.045096. PMID 16339045.
  7. ↑ Tian X, Pascal G, Monget P (2009). "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9: 202. doi:10.1186/1471-2148-9-202. PMC 2735741. PMID 19682372.

Further reading

  • Inohara N, Nuñez G (2003). "NODs: intracellular proteins involved in inflammation and apoptosis". Nat. Rev. Immunol. 3 (5): 371–82. doi:10.1038/nri1086. PMID 12766759.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Tschopp J, Martinon F, Burns K (2003). "NALPs: a novel protein family involved in inflammation". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287.


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