N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase

N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase
Identifiers
EC number 2.4.1.187
CAS number 118731-82-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase (EC 2.4.1.187, uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase, N-acetylmannosaminyltransferase, UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase, UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase) is an enzyme with systematic name UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol 4-beta-N-acetylmannosaminyltransferase.[1] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol UDP + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyldiphosphoundecaprenol

This enzyme is involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls.

References

  1. ↑ Murazumi, N.; Kumita, K.; Araki, Y.; Ito, E. (1988). "Partial purification and properties of UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase from Bacillus subtilis". J. Biochem. 104 (6): 980–984. PMID 2977387.
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