Mefruside

Mefruside
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	C03BA05 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 4-chloro-N1-methyl-N1-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide;
CAS Number	7195-27-9 ;
PubChem CID	4047;
ChemSpider	3907 ;
UNII	X1NS9SNS92;
KEGG	D01877 ;
ECHA InfoCard	100.027.785
Chemical and physical data
Formula	C13H19ClN2O5S2
Molar mass	382.88 g/mol
3D model (JSmol)	Interactive image;
	SMILES CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N;
	InChI InChI=1S/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,18) ; Key:SMNOERSLNYGGOU-UHFFFAOYSA-N ;
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Mefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.^[1]

It was developed by Bayer A.G. and is sold under the tradename Baycaron.

References

↑ Allen HB, Lee DA (1973). "A general practice assessment of mefruside ('Baycaron') in the treatment of oedema and hypertension". Curr Med Res Opin. 1 (9): 547–53. doi:10.1185/03007997309111720. PMID 4779251.

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Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C03BA05 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 4-chloro-N¹-methyl-N¹-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide
CAS Number	7195-27-9^Y
PubChem CID	4047
ChemSpider	3907^N
UNII	X1NS9SNS92
KEGG	D01877^Y
ECHA InfoCard	100.027.785
Chemical and physical data
Formula	C₁₃H₁₉ClN₂O₅S₂
Molar mass	382.88 g/mol
3D model (JSmol)	Interactive image
SMILES CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
InChI InChI=1S/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,18)^N Key:SMNOERSLNYGGOU-UHFFFAOYSA-N^N
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