Markus Affolter

Markus Affolter
Markus Affolter (2011)
Nationality Swiss
Scientific career
Fields Developmental Biologist
Institutions ETH Zurich, Laval University, Biozentrum University of Basel

Markus Affolter is a Swiss Developmental Biologist and Professor at the Biozentrum University of Basel, Switzerland.

Life

Markus Affolter studied Biology at the ETH Zurich and at Laval University in Quebec City, Canada. Following his PhD from Laval University in 1988, he worked as a postdoctoral fellow at the Biozentrum, University of Basel. In the laboratory of Professor Walter Gehring, Markus Affolter began his research with the fruit fly Drosophila melanogaster. In 2000 he became Assistant Professor and in 2005 Professor of Developmental Biology at the Biozentrum, University of Basel.[1]

Work

Markus Affolter researches into the cellular and molecular processes involved in the formation of organs and blood vessel networks in the fruit fly Drosophila melanogaster and zebrafish. Markus Affolter has extensively used live-imaging, high-resolution microscopy in studying network formation in Drosophila and zebrafish. This now enables the better understanding of the function of molecules in morphogenesis. Furthermore, his lab has shown, in collaboration with the University of Freiburg, Germany and the University of Lausanne, that the morphogen Dpp and the feedback regulator Pentagone take on key functions in proportional tissue growth (scaling) in the wing disc of the fruit fly.[2]

Awards and honors

  • 1983: K.M. Hunter Award from the National Cancer Institute of Canada [3]
  • 1999: Elected member of the European Molecular Biology Organization (EMBO) [4]
  • 2008: Elected member of the National Academy of Sciences Leopoldina [5]

References

  1. Curriculum Vitae
  2. Research Group
  3. K.M. Hunter Award National Cancer Institutes of Canada
  4. Affolter, M; Marty, T; Vigano, MA; Jaźwińska, A. "Nuclear interpretation of Dpp signaling in Drosophila". EMBO J. 20: 3298–305. doi:10.1093/emboj/20.13.3298. PMC 125521. PMID 11432817.
  5. National Academy of Sciences Leopoldina
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