MPHOSPH8

MPHOSPH8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LWE, 3QO2, 3R93, 3SVM
Identifiers
Aliases	MPHOSPH8, HSMPP8, TWA3, mpp8, M-phase phosphoprotein 8
External IDs	MGI: 1922589 HomoloGene: 11380 GeneCards: MPHOSPH8
Gene location (Human)
Chr.	Chromosome 13 (human)[1]
End	19,673,459 bp[1]
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)[2]
End	56,697,430 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• methylated histone binding; • protein binding; • ubiquitin protein ligase binding; • ubiquitin-protein transferase activity;
Cellular component	• cytoplasm; • nuclear heterochromatin; • nuclear nucleosome; • plasma membrane; • nucleolus; • cell nucleus; • chromosome; • ubiquitin ligase complex; • cytosol;
Biological process	• regulation of DNA methylation; • negative regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	54737
	75339
	ENSG00000196199
	ENSMUSG00000079184
	Q99549
	Q3TYA6
	NM_017520
	NM_023773; NM_001360072
	NP_059990
	NP_076262; NP_001347001
	Wikidata
View/Edit Human	View/Edit Mouse

M-phase phosphoprotein 8 is an enzyme that in humans is encoded by the MPHOSPH8 gene.^[5]^[6]

References

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika. 42 (2): 274–7. PMID 16583711.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Umeda M, Nishitani H, Nishimoto T (2003). "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM". Gene. 303: 47–54. doi:10.1016/S0378-1119(02)01153-8. PMID 12559565.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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