Jee Hyun Kim

Jee Hyun Kim
Associate Professor Jee Hyun Kim, Head of Developmental Psychobiology Lab at the Florey Institute of Neuroscience & Mental Health
Residence Melbourne, Australia
Nationality Australian
Alma mater University of New South Wales
Scientific career
Fields Neuroscience
Institutions Florey Institute of Neuroscience and Mental Health

Jee Hyun Kim, is an Australian behavioral neuroscientist whose work focuses on emotional learning and memory during childhood and adolescence. She is an associate professor, principal research fellow and head of the Developmental Psychobiology Laboratory at the Florey Institute of Neuroscience and Mental Health in Melbourne, Australia.[1]

Kim is an active science communicator, and has given public lectures at TEDx Melbourne,[2] Australian Museum, National Portrait Gallery, Victorian Science Week, City of Melbourne (Melbourne Conversations[3]), and the Wheeler Center.[4] She has also interviewed for ABC Radio,[5] Radio New Zealand,[6] SBS TV, Channel 10 (The Project[7]).

Research

Jee Hyun Kim's research has demonstrated that the acquisition and retrieval of fear memories is different across childhood, adolescence, and adulthood, and that fear memories are able to be erased early in life. Kim’s research uses rodent models that closely resemble human behaviors to understand the neurobiological basis of those behaviors. Specifically, her work investigates the role of memory and forgetting in the development and treatment of two major mental disorders across childhood and adolescence: anxiety disorder and substance use disorder. Kim has 55 original publications to date, and her work has been cited in other publications over 1600 times.[8]

To study anxiety, the Kim laboratory employs a classical conditioning paradigm based on the work of Ivan Pavlov known as fear conditioning. Despite originating 100 years ago, this model is widely used by modern scientists to uncover the neural mechanisms of fear and anxiety. To investigate substance abuse the Kim laboratory uses a operant conditioning paradigm based on the work of B. F. Skinner known as intravenous self-administration (IVSA). Kim's research especially focuses on extinction, a form of inhibitory learning that forms the basis of exposure-based therapies for both anxiety and addiction disorders.

Career

Kim completed her undergraduate degree at the University of New South Wales (UNSW) in 2004, graduating with the prestigious University Medal in Psychology. She completed her PhD in Psychology in 2008 at UNSW, during which time she published six original scientific articles.[9][10][11][12][13][14] After graduating, Kim worked as a postdoctoral research fellow at UNSW, and then the University of Michigan. Kim then gained a position as a Senior Research Officer at the Florey Institute, before becoming head of the Developmental Psychobiology Laboratory at the institute.

Editor

  • Behavioural Brain Research, Invited Guest Editor for 2016 special issue “Developmental Regulation of Memory in Anxiety and Addiction”
  • Frontiers in Behavioral Neuroscience, Review Editor
  • Frontiers in Translational Pharmacology, Review Editor
  • Neurotransmitter, Associate Editor
  • Pharmacology Research & Perspectives, Associate Editor

Leadership and Committees

Kim is Co-chair of the Florey Graduate Research Committee, which provides leadership to over 200 graduate research students at the institute. Kim has served as a mentor for the Florey student association, Students of Florey Institutes (SoFI), and has been an invited speaker for Florey Mentor/Mentee Workshops.

Kim is a vocal advocate for Women in Science, and has served on the committee for the Florey Committee for Equality is Science (EqIS).[15] Kim was acknowledged for her role as a proponent for women in science in the manuscript of Kate White’s book, 'Building effective career paths for women in science research: a case study of an Australian science research institute'.[16] Kim has completed the National Australian Bank “Realise” female leadership program, and attended “The X-factor: Putting Sex and Gender Under the Microscope in Medical Research” meeting hosted by Perpetual & Women Donors.

Kim is a member of the Florey Animal Ethics Committee, which is committed to maintaining ethical standards in the use of animals in neuroscientific research at the Florey Institute of Neuroscience & Mental Health. Kim is also a board member for the International Society for Developmental Psychobiology, and has been a Symposium Organiser and Chair at several international scientific conferences. Kim is the treasurer of Biological Psychiatry Australia.[17] Kim is a grant reviewer for both the NHMRC and the ARC, and a member of the NHMRC Research Translation Faculty.

Awards

Publications

Highlights

Year Title Contributor(s) Journal Highlights and notes DOI
2016 The role of dopamine 2 receptor in impaired drug-cue extinction in adolescent rats Zbukvic IC, Ganella DE, Perry C, Madsen H, Bye C, Lawrence AJ, & Kim JH Cerebral Cortex. 26: 2895-2904. Cocaine-associated cue extinction reduced cue-induced reinstatement in adult but not adolescent rats. Infusion of the selective dopamine 2 receptor (D2R)-like agonist quinpirole into the infralimbic cortex (IL) of the mPFC prior to cue extinction significantly reduced cue-induced reinstatement in adolescents. This effect was replicated by systemic treatment with aripiprazole. These findings inspire new tactics for improving adolescent cue exposure therapy.[29]
2015 Extinction of a cocaine-taking context that protects against drug-primed reinstatement is dependent on the metabotropic glutamate 5 receptor. . Kim JH, Perry C, Luikinga S, Zbukvic I, Brown RM, & Lawrence AJ Addiction Biology. 20: 482-489.
2015 Early life stress alters pituitary growth during adolescence – a longitudinal study. Ganella DE, Allen NB, Simmons JG, Schwartz O, Kim JH, Sheebar L, & Whittle S Psychoneuroendocrinology. 53: 185-194
2014 Developmental rodent models of fear and anxiety: From neurobiology to pharmacology. . Ganella DE & Kim JH British Journal of Pharmacology. 171: 4556-4574 Won The Florey Institute best review
2014 The effects of mGlu5 negative allosteric modulator MTEP and NMDA receptor partial agonist D-cycloserine on Pavlovian conditioned fear. Handford CE, Tan S, Lawrence AJ, & Kim JH International Journal of Neuropsychopharmacology, 17: 1521-1532
2014 Knockdown of CRF1 receptors in the ventral tegmental area attenuates cue- and acute food deprivation stress-induced cocaine-seeking in mice. Chen N, Jupp B, Sztainberg Y, Brown RM, Kim JH, Chen A, Lawrence AJ Journal of Neuroscience. 34: 11560-11570 "This week in the journal” article
2011 Hippocampal and prefrontal projections to the basal amygdala mediate contextual regulation of fear after extinction. Orsini CA, Kim JH, Knapska E, Maren S Journal of Neuroscience, 31: 17269-17277
2011 Immunohistochemical analyses of extinction of conditioned fear in adolescent rats. Kim JH, Li S & Richardson R Cerebral Cortex, 21: 530-538.
2010 New findings on extinction of conditioned fear early in development: Theoretical and clinical implications. Kim JH & Richardson R Biological Psychiatry, 67: 297-303.
2009 Fear extinction across development: the involvement of the medial prefrontal cortex as assessed by temporary inactivation and immunohistochemistry. Kim JH, Hamlin AS & Richardson R Journal of Neuroscience, 29: 10802-10808 “This week in the journal” article
2008 The effect of temporary amygdala inactivation on extinction and re-extinction of fear in the developing rat: Unlearning as a potential mechanism for extinction early in development. Journal of Neuroscience, 28: 1282-1290. Kim JH & Richardson R Journal of Neuroscience, 28: 1282-1290. “This week in the journal” article

Other journal articles

Year Title Contributor(s) Journal Highlights and notes DOI
2018 Neurocircuitry of fear extinction in adult and juvenile rats Ganella DE, Nguyen LD, Lee-Kardashyana L, Kim LE, Paolini AG, Kim JH Behavioural Brain Research. In press. Anxiety. Juveniles and adults rats have comparable basolateral amygdala (BLA) projections to the hippocampus and to the infralimbic cortex. Adults rats show activated BLA cells projecting to hippocampus after extinction. Activated BLA projections correlate with behavior in adults but not in juveniles rats.[30]
2018 Extinction of conditioned fear in adolescents and adults: a human fMRI study Ganella DE, Drummond K, Ganella EP, Whittle S & Kim JH Frontiers in Human Neuroscience. In press. Anxiety. Healthy adolescent humans show different behavioral responses, and dampened prefrontal cortex (PFC) activity during short-term extinction recall compared to healthy adults. Posterior cingulate cortex (PCC), and temporoparietal junction (TPJ) were identified as novel regions that may be associated with impaired extinction in adolescents. This study highlights adolescent-specific neural correlates of extinction, which may explain the peak in prevalence of anxiety disorders during adolescence.[31]
2018 Prefrontal-Amygdala Connectivity and State Anxiety during Fear Extinction Recall in Adolescents Ganella DE, Barendse MEA, Kim JH, & Whittle S Frontiers in Human Neuroscience. In press. Anxiety. Fear extinction recall in healthy adolescents is associated with functional connectivity between prefrontal and limbic brain regions, and suggest that alterations in connectivity may be associated with vulnerability to anxiety in adolescence.[32]
2018 Divergent prefrontal dopaminergic mechanisms mediate drug- and fear-associated cue extinction during adolescence versus adulthood Zbukvic IC, & Kim JH European Neuropsychopharmacology. In press Anxiety & Addiction. Review summarizing evidence from animal and human literature that cue extinction is critically mediated by prefrontal dopamine, a system that undergoes dramatic reorganization during adolescence.[33]
2017 Developmental perspectives on methamphetamine abuse: Exploring adolescent vulnerabilities on brain and behavior Luikinga SJ, Kim JH, & Perry CJ Progress in Neuropsychopharmacology & Biological Psychiatry. In press. Addiction. Methamphetamine use usually begins in adolescence, and earlier onset is associated with increased risk of developing a substance use disorder. Methamphetamine exposure causes volumetric and neurotransmitter changes in regions that are developing during adolescence. Dopamine cell loss following acute meth exposure is lower in adolescents than adults.[34]
2017 Juvenile female rats, but not male rats, show renewal, reinstatement, and spontaneous recovery following extinction of conditioned fear Park JCH, Ganella DE, & Kim JH Learning & Memory. In press. Anxiety. Fear regulation appear to be different in males versus females from early in development, which may explain why girls are more prone to suffer from anxiety disorders compared to boys.[35]
2017 Investigating the role of dopamine receptor- and parvalbumin-expressing cells in extinction of conditioned fear Madsen HB, Guerin A, Kim JH Neurobiology of Learning and Memory. 145: 7-17 Anxiety. Extinction increased Fos+ and decreased D2R+ cells in the infralimbic cortex. Fear retrieval increased Fos labeling of D2R+ cells in the prelimbic cortex. Context exposure, retrieval, and extinction display overlapping neural activation.[36]
2017 Aripiprazole facilitates extinction of conditioned fear in adolescent rats Ganella DE, Lee-Kardashyan L, Luikinga SJ, Nguyen DLD, Madsen HB, Zbukvic IC, Coulthard R, Lawrence AJ, & Kim JH Frontiers in Behavioral Neuroscience. 11: 76. Anxiety. Aripiprazole represents a novel pharmacological adjunct to exposure therapy worthy of further examination. The effect of aripiprazole is related to enhanced activation of mPFC neurons receiving dopaminergic innervation.[37]
2017 A dissociation between renewal and contextual fear conditioning in juvenile rats Park JCH, Ganella DE, & Kim JH Developmental Psychobiology. 59: 515-522 Anxiety. Results of this study indicate that the developmental dissociation observed in renewal of extinguished fear may not related to the widely believed late emergence of contextual fear learning.[38]
2017 Prefrontal dopaminergic mechanisms of fear extinction in adolescence compared to adulthood in rats Zbukvic IC, Park JCH, Ganella DE, Lawrence AJ, & Kim JH Frontiers in Behavioral Neuroscience. 11: 32 Anxiety.
2017 Extinction of conditioned cues attenuates incubation of craving in adolescent and adult rats Madsen HB, Zbukvic IC, Luikinga SJ, Lawrence AJ, & Kim JH Neurobiology of Learning and Memory. 143: 88-93 Addiction. Adolescent and adult rats self-administer similar amounts of cocaine. Adolescent rats are impaired in lever discrimination for cocaine Incubation of cocaine-seeking was similar in adolescent and adult rats. Aripiprazole injection did not facilitate cue extinction.[39]
2017 In vivo prion models and the disconnection between transmissibility versus neurotoxicity Senesi M, Lewis V, Kim JH, Adlard P, Finkelstein DI, & Collins SJ Ageing Research Reviews. 36: 156-164 Separate species of PrPSc underpinning prion transmission and neurotoxicity is under debate. Potential new target for treatment can be defined for each of the species. Novel animal modelling may uncover other factors influencing prion disease pathogenesis.[40]
2017 Exercise alters mouse sperm microRNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety Short AK, Yeshurun S, Powell R, Perreau VM, Fox A, Kim JH, Pang TY, & Hannan AJ Translational Psychiatry. 7: e1114 Anxiety.
2017 Reducing fear during childhood to prevent anxiety disorders later: Insights from developmental psychobiology Kim JH Policy Insights from the Behavioral and Brain Sciences. 4, 131-138 Anxiety. Anxiety disorders are neurodevelopmental with the median age of onset 10 to 11 years. Extinction processes that are involved in cognitive-behavioral therapy appear particularly effective in children compared with older populations. Policy should mandate school psychologists and government subsidies for therapy sessions to increase children’s mental-health-service utilization.[41]
2017 Postnatal development of neurotransmitter systems and their relevance to extinction of conditioned fear Kim JH, Perry CJ, Ganella DE, Madsen HB Neurobiology of Learning and Memory. 138: 252-270 Anxiety. Relapse-resistant extinction in juvenile rodents may be due to high NMDA-NR2B, mGlu5, and/or nicotinic receptor signaling in the amygdala. Extinction deficit in adolescence may be due to low NMDA-NR2B, and/or low D2R relative to D1R signaling in the PFC.Changes in the localization of oxytocin receptors in the amygdala may explain transition from effective to ineffective extinction across development.[42]
2016 Knockdown of corticotropin-releasing factor 1 receptors in the ventral tegmental area enhances conditioned fear Chen NA, Ganella DE, Bathgate R, Chen A, Lawrence AJ, & Kim JH European Neuropsychopharmacology. 26: 1533-1540. Anxiety.
2016 Fear extinction in 17 day old rats is dependent on metabotropic glutamate receptor 5 signaling Ganella DE, Thangaraju P, Lawrence AJ, & Kim JH Behavioural Brain Research. 298: 32-36. Anxiety. Positive allosteric modulation of mGlu5 facilitates extinction of conditioned fear in postnatal day (P) 17 rats, but not in P24 or adult rats. Negative allosteric modulation of Glu5 impairs extinction of conditioned fear in P17 rats, but not in P24 or adult rats. There is a developmental shift in the importance of mGlu5 signaling in extinction of conditioned fear.[43]
2016 Elevated paternal glucocorticoid levels alter the sperm microRNA profile and modify offspring anxiety and depressive phenotypes Short AK, Fennell KA, Perreau VM, Fox A, O’Bryan MK, Kim JH, Bredy TW, Pang TY, & Hannan AJ Translational Psychiatry. 6: e837 Paternal corticosterone administration in mice alters offspring body weights. Paternal corticosterone administration alters cognitive performance of female offspring. Stress-associated transgenerational epigenetic inheritance impacts cognition and behaviour.[44]
2016 The effects of 4-methylethcathinone on CPP, locomotor sensitization, and anxiety-like behaviour: a comparison with methamphetamine Xu P, Qiu Y, Zhang Y, Bai Y, Xu P, Liu Y, Kim JH, & Shen H International Journal of Neuropsychopharmacology. 19: 1-7 Addiction.
2016 Orexin-1 receptor signalling in the pre-limbic cortex regulates cue-induced reinstatement of ethanol-seeking in iP rats Brown RM, Kim A, Khoo S, Kim JH, Jupp B, Lawrence AJ Addiction Biology. 21: 603-612 Addiction.
2016 The metabotropic glutamate 5 receptors is necessary for extinction of cocaine-associated cues Perry CJ, Reed F, Zbukvic IC, Kim JH, & Lawrence AJ British Journal of Pharmacology. 173: 1085-1094 Addiction.
2016 Adenosine 2A receptors modulate reward behaviours for methamphetamine Chesworth R, Brown R, Kim JH, Ledent C, & Lawrence AJ Addiction Biology. 21: 407-421 Addiction.
2016 Youth is not wasted on the young: Commentary on a BBR themed issue on developmental regulation of memory in anxiety and addiction Kim JH Behavioural Brain Research. 298: 1-3 Anxiety & Addiction.
2016 Ontogeny of memory: An update on 40 years of work on infantile amnesia Madsen HB & Kim JH Behavioural Brain Research. 298: 4-14 Anxiety. Infantile amnesia is the phenomenon of accelerated forgetting in young animals. The neurobiological causes of infantile amnesia appear to be multifaceted. Late development of the hippocampus, amygdala and prefrontal cortex all contribute. Developmental changes in neurotransmitter systems also appear to be involved.[45]
2015 Spatial learning requires mGlu5 signalling in the dorsal hippocampus Tan SZK, Ganella DE, Dick A, Duncan JR, Ong-Palsson E, Bathgate R, Kim JH, & Lawrence AJ Neurochemical Research. 40: 1303-1310
2015 A review of preclinical studies to understand fear during adolescence Kim JH & Ganella DE Australian Psychologist. 50: 25-31 Anxiety.
2014 Drugs currently in phase II trials for cocaine addiction Kim JH, & Lawrence AJ Expert Opinion On Investigational Drugs. 23: 1105-1122 Addiction. Amphetamine salts and topiramate stand out in terms of their potential efficacy in treating cocaine addiction. The efficacy of topiramate was closely associated with regular cognitive-behavioural therapy (CBT), which highlights the importance of a combined effort to promote abstinence and enhance retention via CBT. Cognitive/psychological screening appears necessary for a more symptom-based approach with more reasonable outcomes other than abstinence (e.g., improved quality of life) in treating cocaine addiction.
2014 The role of cues and contexts on drug-seeking behaviour Perry C, Zbukvic I, Kim JH, & Lawrence AJ British Journal of Pharmacology. 171: 4636-4672 Addiction.
2014 Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine Kim JH, Lavan D, Chen N, Flores C, Cooper H, & Lawrence AJ Psychopharmacology, 230: 607-616 Addiction.
2013 The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice Chesworth R, Brown RM, Kim JH, & Lawrence AJ PLOS One. 8: e68371 Addiction.
2012 Phosphorylation of mitogen-activated protein kinase in the medial prefrontal cortex and the amygdala following memory retrieval or forgetting in developing rats Kim JH, Li S, Hamlin AS, McNally GP, & Richardson R Neurobiology of Learning & Memory, 97: 59-68 Anxiety.
2012 Updating memories: Changing the involvement of the prelimbic cortex in the expression of an infant fear memory Li S, Kim JH, & Richardson R Neuroscience, 222: 316-325 Anxiety.
2012 Differential involvement of the medial prefrontal cortex in the expression of learned fear across development Li S, Kim JH, & Richardson R Behavioral Neuroscience, 126: 217-225 Anxiety.
2012 Impaired extinction retention in adolescent rats: effects of D-cycloserine McCallum J, Kim JH & Richardson R Neuropsychopharmacology, 35: 2134-2142 Anxiety.
2010 Extinction in preweanling rats does not involve NMDA receptors Kim JH & Richardson R Neurobiology of Learning & Memory, 94: 176-182 Anxiety.
2009 Expression of renewal is dependent on the extinction-test interval rather than the acquisition-extinction interval Kim JH & Richardson R Behavioral Neuroscience, 123: 641-649 Anxiety.
2009 The effect of the μ-opioid receptor antagonist naloxone on extinction of conditioned fear in the developing rat Kim JH & Richardson R Learning & Memory, 16: 161-166 Anxiety.
2007 The effect of the NMDA receptor antagonist MK-801 on the acquisition and extinction of learned fear in the developing rat Langton JM, Kim JH, Nicholas J & Richardson R Learning & Memory, 14: 665-668 Anxiety.
2007 Immediate post-reminder injection of gamma-amino butyric acid agonist mida-zolam attenuates reactivation of forgotten fear in the infant rat Kim JH & Richardson R Behavioral Neuroscience, 121: 1328 -1332 Anxiety.
2007 A developmental dissociation in reinstatement of an extinguished fear response in rats Kim JH & Richardson R Neurobiology of Learning & Memory, 88: 48-57 Anxiety.
2007 A developmental dissociation of context and GABA effects on extinguished fear in rats Kim JH & Richardson R Behavioral Neuroscience, 121: 131-139 Anxiety.
2006 Recovery of fear memories in rats: role of gamma-aminobutyric acid in infantile amnesia Kim JH, McNally GP, & Richardson R Behavioral Neuroscience, 120: 40-48 Anxiety.

Book chapters

Year Title Contributors Book Editor
2013 Preclinical analysis of developmental transitions in the extinction of learned fear: from infancy through adolescence to adulthood Callaghan BL, Li S, Kim JH & Richardson R Changing Emotions. Psychology Press: London. pp. 81-87 D. Hermans, B. Rimé, & B. Mesquita
2012 The role of metabotropic glutamate 5 receptor in drug addiction Kim JH & Lawrence AJ Emerging Targets for Drug Addiction Treatment. NOVA publishers: New York. pp. 183-202 J.J. Canales
2012 The role of mitogen-activated protein kinase in treatment strategies for fear and drug addiction Brown RM, Lawrence AJ & Kim JH Advances in Protein Kinases. InTech: Rijeka, Croatia. pp. 333-374. G. Da Silva Xavier

Articles

"The Conversation". Comic explainer: how memory works. 2016.

"The Conversation". Breed scientists better for a better breed of science. 2013.

"The Conversation". Going, going, gone: the where and why of memory erasure. 2013.

"The Conversation". Explainer: what is forgetting?. 2013.

"The Conversation". Explainer: what is memory?. 2012.

References

  1. ↑ "Dr Jee Hyun Kim | The Florey Institute of Neuroscience and Mental Health". www.florey.edu.au. Retrieved 2015-11-24.
  2. ↑ TEDxMelbourne. "Living Without Fear: Dr Jee Hyun Kim". YouTube. TEDx.
  3. ↑ City of Melbourne. "Science City - Has Melbourne got what it takes?". Melbourne Conversations. YouTube.
  4. ↑ "Forget About It!: The Science and Psychology of Memory". The Wheeler Centre. Retrieved 2017-08-25.
  5. ↑ Australian Broadcasting Corporation. "Jee Hyun Kim studies the science and mysteries of memory". Conversations with Richard Fidler.
  6. ↑ Radio New Zealand. "Jee Hyun Kim - Neuroscientist specialising in memory". Radio New Zealand National.
  7. ↑ Channel 10. "Memory by Dr. Jee Hyun Kim". YouTube. The Project.
  8. ↑ "Jee Hyun Kim - Google Scholar Citations". scholar.google.com.au. Retrieved 2017-10-06.
  9. ↑ Kim, Jee Hyun; McNally, Gavan P.; Richardson, Rick (2006-02-01). "Recovery of fear memories in rats: role of gamma-amino butyric acid (GABA) in infantile amnesia". Behavioral Neuroscience. 120 (1): 40–48. doi:10.1037/0735-7044.120.1.40. ISSN 0735-7044. PMID 16492115.
  10. ↑ Kim, Jee Hyun; Richardson, Rick (2007-02-01). "A developmental dissociation of context and GABA effects on extinguished fear in rats". Behavioral Neuroscience. 121 (1): 131–139. doi:10.1037/0735-7044.121.1.131. ISSN 0735-7044. PMID 17324057.
  11. ↑ Kim, Jee Hyun; Richardson, Rick (2007-07-01). "A developmental dissociation in reinstatement of an extinguished fear response in rats". Neurobiology of Learning and Memory. 88 (1): 48–57. doi:10.1016/j.nlm.2007.03.004. ISSN 1074-7427. PMID 17459734.
  12. ↑ Kim, Jee Hyun; Richardson, Rick (2007-12-01). "Immediate post-reminder injection of gamma-amino butyric acid (GABA) agonist midazolam attenuates reactivation of forgotten fear in the infant rat". Behavioral Neuroscience. 121 (6): 1328–1332. doi:10.1037/0735-7044.121.6.1328. ISSN 0735-7044. PMID 18085885.
  13. ↑ Langton, Julia M.; Kim, Jee Hyun; Nicholas, Jennifer; Richardson, Rick (2007-10-01). "The effect of the NMDA receptor antagonist MK-801 on the acquisition and extinction of learned fear in the developing rat". Learning & Memory (Cold Spring Harbor, N.Y.). 14 (10): 665–668. doi:10.1101/lm.692407. ISSN 1549-5485. PMID 17909101.
  14. ↑ Kim, Jee Hyun; Richardson, Rick (2008-02-06). "The Effect of Temporary Amygdala Inactivation on Extinction and Reextinction of Fear in the Developing Rat: Unlearning as a Potential Mechanism for Extinction Early in Development". The Journal of Neuroscience. 28 (6): 1282–1290. doi:10.1523/JNEUROSCI.4736-07.2008. ISSN 0270-6474. PMID 18256248.
  15. ↑ "Equality in Science | The Florey Institute of Neuroscience and Mental Health". www.florey.edu.au. Retrieved 2015-11-25.
  16. ↑ White, Kate. "Federation University Australia". federation.edu.au. Retrieved 2015-11-25.
  17. ↑ "About Us – Biological Psychiatry Australia". Biological Psychiatry Australia. Retrieved 2017-08-25.
  18. ↑ "Aubrey Lewis Award – Biological Psychiatry Australia". Biological Psychiatry Australia. Retrieved 2017-12-08.
  19. ↑ "2016 Award Winners | CINP". cinp.org. Retrieved 2017-01-31.
  20. ↑ "Dr Jee Hyun Kim | AIPS". www.aips.net.au. Retrieved 2015-11-24.
  21. ↑ "International Society for Developmental Psychobiology". 46th Annual Meeting Conference Program. ISDP.
  22. ↑ "Australian Psychological Society : Early Career Research Awards". www.psychology.org.au. Retrieved 2015-11-25.
  23. ↑ "D.G. Marquis Behavioral Neuroscience Award". www.apadivisions.org. American Psychological Association. Retrieved 2015-11-25.
  24. ↑ "Richardson Lab - Home". www2.psy.unsw.edu.au. Retrieved 2015-11-25.
  25. ↑ "International Society for Developmental Psychobiology" (PDF). 42nd Annual Meeting Conference Program. ISDP.
  26. ↑ "Australian Psychological Society : Award for Excellent PhD Thesis in Psychology". www.psychology.org.au. Retrieved 2015-11-25.
  27. ↑ "International Society for Developmental Psychobiology". 40th Annual Meeting Conference Programme. ISDP.
  28. ↑ "Australian Psychological Society : APS Prize". www.psychology.org.au. Retrieved 2015-11-25.
  29. ↑ Zbukvic, Isabel C.; Ganella, Despina E.; Perry, Christina J.; Madsen, Heather B.; Bye, Christopher R.; Lawrence, Andrew J.; Kim, Jee Hyun (2016-06-01). "Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats". Cerebral Cortex. 26 (6): 2895–2904. doi:10.1093/cercor/bhw051. ISSN 1047-3211. PMC 4869820.
  30. ↑ Ganella, Despina E.; Nguyen, Ly Dao; Lee-Kardashyan, Liubov; Kim, Leah E.; Paolini, Antonio G.; Kim, Jee Hyun (October 2018). "Neurocircuitry of fear extinction in adult and juvenile rats". Behavioural Brain Research. 351: 161–167. doi:10.1016/j.bbr.2018.06.001. ISSN 0166-4328.
  31. ↑ Ganella, Despina E.; Drummond, Katherine D.; Ganella, Eleni P.; Whittle, Sarah; Kim, Jee Hyun (2018). "Extinction of Conditioned Fear in Adolescents and Adults: A Human fMRI Study". Frontiers in Human Neuroscience. 11. doi:10.3389/fnhum.2017.00647. ISSN 1662-5161.
  32. ↑ Ganella, Despina E.; Barendse, Marjolein E. A.; Kim, Jee H.; Whittle, Sarah (2017). "Prefrontal-Amygdala Connectivity and State Anxiety during Fear Extinction Recall in Adolescents". Frontiers in Human Neuroscience. 11. doi:10.3389/fnhum.2017.00587. ISSN 1662-5161.
  33. ↑ Zbukvic, Isabel C.; Kim, Jee Hyun (2018). "Divergent prefrontal dopaminergic mechanisms mediate drug- and fear-associated cue extinction during adolescence versus adulthood". European Neuropsychopharmacology. 28 (1): 1–12. doi:10.1016/j.euroneuro.2017.11.004.
  34. ↑ Luikinga, Sophia J.; Kim, Jee Hyun; Perry, Christina J. (2017). "Developmental perspectives on methamphetamine abuse: Exploring adolescent vulnerabilities on brain and behavior". Progress in Neuro-Psychopharmacology and Biological Psychiatry. doi:10.1016/j.pnpbp.2017.11.010.
  35. ↑ Park, Chun Hui J.; Ganella, Despina E.; Kim, Jee Hyun (2017-12-01). "Juvenile female rats, but not male rats, show renewal, reinstatement, and spontaneous recovery following extinction of conditioned fear". Learning & Memory. 24 (12): 630–636. doi:10.1101/lm.045831.117. ISSN 1072-0502. PMC 5688961. PMID 29142058.
  36. ↑ Madsen, Heather B.; Guerin, Alexandre A.; Kim, Jee Hyun (2017). "Investigating the role of dopamine receptor- and parvalbumin-expressing cells in extinction of conditioned fear". Neurobiology of Learning and Memory. 145: 7–17. doi:10.1016/j.nlm.2017.08.009.
  37. ↑ Ganella, Despina E.; Lee-Kardashyan, Liubov; Luikinga, Sophia J.; Nguyen, Danny L. D.; Madsen, Heather B.; Zbukvic, Isabel C.; Coulthard, Russell; Lawrence, Andrew J.; Kim, Jee Hyun (2017). "Aripiprazole Facilitates Extinction of Conditioned Fear in Adolescent Rats". Frontiers in Behavioral Neuroscience. 11. doi:10.3389/fnbeh.2017.00076. ISSN 1662-5153.
  38. ↑ Park, Chun Hui J.; Ganella, Despina E.; Kim, Jee Hyun (2017-05-01). "A dissociation between renewal and contextual fear conditioning in juvenile rats". Developmental Psychobiology. 59 (4): 515–522. doi:10.1002/dev.21516. ISSN 1098-2302.
  39. ↑ Madsen, Heather B.; Zbukvic, Isabel C.; Luikinga, Sophia J.; Lawrence, Andrew J.; Kim, Jee Hyun (2016). "Extinction of conditioned cues attenuates incubation of cocaine craving in adolescent and adult rats". Neurobiology of Learning and Memory. 143: 88–93. doi:10.1016/j.nlm.2016.09.002.
  40. ↑ Senesi, Matteo; Lewis, Victoria; Kim, Jee H.; Adlard, Paul A.; Finkelstein, David I.; Collins, Steven J. (2017). "In vivo prion models and the disconnection between transmissibility and neurotoxicity". Ageing Research Reviews. 36: 156–164. doi:10.1016/j.arr.2017.03.007.
  41. ↑ Kim, Jee Hyun (2017-08-24). "Reducing Fear During Childhood to Prevent Anxiety Disorders Later: Insights From Developmental Psychobiology". Policy Insights from the Behavioral and Brain Sciences. 4 (2): 131–138. doi:10.1177/2372732217719544.
  42. ↑ Kim, Jee Hyun; Perry, Christina J.; Ganella, Despina E.; Madsen, Heather B. (2017). "Postnatal development of neurotransmitter systems and their relevance to extinction of conditioned fear". Neurobiology of Learning and Memory. 138: 252–270. doi:10.1016/j.nlm.2016.10.018.
  43. ↑ Ganella, Despina E.; Thangaraju, Pushbalela; Lawrence, Andrew J.; Kim, Jee Hyun (2016). "Fear extinction in 17 day old rats is dependent on metabotropic glutamate receptor 5 signaling". Behavioural Brain Research. 298: 32–36. doi:10.1016/j.bbr.2014.12.010.
  44. ↑ Short, A K; Fennell, K A; Perreau, V M; Fox, A; O’Bryan, M K; Kim, J H; Bredy, T W; Pang, T Y; Hannan, A J (June 2016). "Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring". Translational Psychiatry. 6 (6): e837. doi:10.1038/tp.2016.109. ISSN 2158-3188.
  45. ↑ Madsen, Heather Bronwyn; Kim, Jee Hyun (2016). "Ontogeny of memory: An update on 40 years of work on infantile amnesia". Behavioural Brain Research. 298: 4–14. doi:10.1016/j.bbr.2015.07.030.
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