Iron sucrose

Iron sucrose
Clinical data
Trade names Venofer
AHFS/Drugs.com FDA Professional Drug Information
Pregnancy
category
  • US: B (No risk in non-human studies)
    Routes of
    administration    		 Intravenous
    ATC code
    Legal status
    Legal status
    Chemical and physical data
    Formula [Na2Fe5O8(OH) •3(H2O)]n •m(C12H22O11)
    Molar mass 34,000 to 60,000 g/mol

    Iron sucrose (brand name Venofer) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.[1] It is frequently used in patients undergoing hemodialysis, those undergoing erythropoietin therapy, and/or patients who have chronic kidney disease. It is a type 2 complex which limits the maximum dose that can be given to 1000mg which requires 5-10 administrations. Unlike previous generations of IV iron supplements, this drug does not contain dextran.

    The drug consists of ferric hydroxide solubilized in aqueous sucrose. Upon IV administration, the iron is distributed to ferritin, the normal iron storage protein.[2]

    References

    1. ↑ "Iron Sucrose (Intravenous Route)". Mayo Clinic. Retrieved 22 January 2016.
    2. ↑ Jerry Yee, Anatole Besarab (2002). "In-Depth Review: Iron sucrose: The oldest iron therapy becomes new". American Journal of Kidney Diseases. 40: 1111–1121. doi:10.1053/ajkd.2002.36853.


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