Inosine pranobex

Inosine pranobex
INN: Inosine acedoben dimepranol
Chemical structures of the three components of inosine pranobex
Combination of
Inosine Immunostimulant
Acedoben dimepranol Immunostimulant
Clinical data
Trade names Imunovir, Delimmun, Isoprinosine
Synonyms Methisoprinol
ATC code
Identifiers
PubChem CID
ChemSpider
KEGG
ECHA InfoCard 100.048.313 Edit this at Wikidata

Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. Inosine pranobex has no effect on viral particles itself. Instead, it acts as an immunostimulant, an analog of thymus hormones.[1] It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.[2]

In the UK, inosine pranobex is also indicated for mucocutaneous infections due to herpes simplex virus (type 1 and type 2) and for treatment of genital warts as adjunctive therapy to podophyllin or carbon dioxide laser.[3]

References

  1. ↑ American Cancer Society. "Inosine Pranobex". Archived from the original on 23 August 2010. Retrieved 31 July 2013.
  2. ↑ Campoli-Richards DM, Sorkin EM, Heel RC (Nov 1986). "Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy". Drugs. 32 (5): 383–424. doi:10.2165/00003495-198632050-00001.
  3. ↑ "Imunovir 500mg Tablets". UK Electronic Medicines Compendium.


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