Influenza A virus subtype H1N2

H1N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in both human and pig populations.

H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans.

The virus does not cause more severe illness than other influenza viruses, and no unusual increases in influenza activity have been associated with it.

History

Between December 1988 and March 1989, 19 influenza H1N2 virus isolates were identified in 6 cities in China, but the virus did not spread further.[1]

A(H1N2) was identified during the 2001–02 flu season (northern hemisphere) in Canada, the U.S., Ireland, Latvia, France, Romania, Oman, India, Malaysia, and Singapore with earliest documented outbreak of the virus occurring in India on May 31, 2001.

On February 6, 2002, the World Health Organization (WHO) in Geneva and the Public Health Laboratory Service (PHLS) in the United Kingdom reported the identification influenza A(H1N2) virus from humans in the UK, Israel, and Egypt.

The 2001–02 Influenza A(H1N2) Wisconsin strain appears to have resulted from the reassortment of the genes of the currently circulating influenza A(H1N1) and A(H3N2) subtypes.

Because the hemagglutinin protein of the virus is similar to that of the currently circulating A(H1N1) viruses and the neuraminidase protein is similar to that of the current A(H3N2) viruses, the seasonal flu vaccine should provide good protection against influenza virus as well as protection against the currently circulating seasonal A(H1N1), A(H3N2), and B viruses.

Between December 2010 and January 2011, there have been cases in China, but the virus is spreading further. 19 people have died, while tens of thousands are currently sick.

New case of H1N2 was found on a Minnesota baby in December 2011.[2]

References

  1. ↑ Guo, YJ; Xu, XY; Cox, NJ (1992). "Human influenza A (H1N2) viruses isolated from China". The Journal of General Virology. 73 (2): 383–7. doi:10.1099/0022-1317-73-2-383. PMID 1538194
  2. ↑ "Infant In Minn. Develops H1N2, Unique Type Of H1N1". WCCO. Retrieved 9 January 2013.

  • Choi YK, Goyal SM, Farnham MW, Joo HS (August 2002). "Phylogenetic analysis of H1N2 isolates of influenza A virus from pigs in the United States". Virus Res. 87 (2): 173–9. doi:10.1016/S0168-1702(02)00053-9. PMID 12191781.
  • CDC. "Information on Avian Influenza".
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