ITIH4

ITIH4
Identifiers
AliasesITIH4, GP120, H4P, IHRP, ITI-HC4, ITIHL1, PK-120, PK120, inter-alpha-trypsin inhibitor heavy chain family member 4
External IDsMGI: 109536 HomoloGene: 1670 GeneCards: ITIH4
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p21.1Start52,812,975 bp[1]
End52,831,479 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

3700

16427

Ensembl

ENSG00000055955

ENSMUSG00000021922

UniProt

Q14624

A6X935

RefSeq (mRNA)

NM_002218
NM_001166449

NM_001159299
NM_001289632
NM_001289633
NM_018746

RefSeq (protein)

NP_001159921
NP_002209

NP_001152771
NP_001276561
NP_001276562
NP_061216

Location (UCSC)Chr 3: 52.81 – 52.83 MbChr 14: 30.89 – 30.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Inter-alpha-trypsin inhibitor heavy chain H4 is a protein that in humans is encoded by the ITIH4 gene.[5][6][7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000055955 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021922 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Soury E, Olivier E, Daveau M, Hiron M, Claeyssens S, Risler JL, Salier JP (Mar 1998). "The H4P heavy chain of inter-alpha-inhibitor family largely differs in the structure and synthesis of its prolin-rich region from rat to human". Biochem Biophys Res Commun. 243 (2): 522–30. doi:10.1006/bbrc.1998.8128. PMID 9480842.
  6. ↑ Nishimura H, Kakizaki I, Muta T, Sasaki N, Pu PX, Yamashita T, Nagasawa S (Feb 1995). "cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein". FEBS Lett. 357 (2): 207–11. doi:10.1016/0014-5793(94)01364-7. PMID 7805892.
  7. ↑ "Entrez Gene: ITIH4 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)".

Further reading

  • Choi-Miura NH, Sano Y, Oda E, et al. (1995). "Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma". J. Biochem. 117 (2): 400–7. doi:10.1093/jb/117.2.400. PMID 7541790.
  • Tobe T, Saguchi K, Hashimoto K, et al. (1995). "Mapping of human inter-alpha-trypsin inhibitor family heavy chain-related protein gene (ITIHL1) to human chromosome 3p21→p14". Cytogenet. Cell Genet. 71 (3): 296–8. doi:10.1159/000134130. PMID 7587397.
  • Saguchi K, Tobe T, Hashimoto K, et al. (1995). "Cloning and characterization of cDNA for inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein". J. Biochem. 117 (1): 14–8. PMID 7775381.
  • Saguchi K, Tobe T, Hashimoto K, et al. (1997). "Isolation and characterization of the human inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene (ITIHL1)". J. Biochem. 119 (5): 898–905. doi:10.1093/oxfordjournals.jbchem.a021327. PMID 8797089.
  • Jean L, Smih F, Olivier E, et al. (1997). "Comparative assignments of the genes of the inter-alpha-inhibitor family in human and mouse: ITIH4 is close to ITIH1 and ITIH3, on HSA 3 and MMU 14". Genomics. 41 (1): 139–40. doi:10.1006/geno.1997.4612. PMID 9126497.
  • Diarra-Mehrpour M, Sarafan N, Bourguignon J, et al. (1998). "Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage". J. Biol. Chem. 273 (41): 26809–19. doi:10.1074/jbc.273.41.26809. PMID 9756925.
  • Tozaki T, Choi-Miura NH, Taniyama M, et al. (2003). "SNP analysis of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene by a fluorescence-adapted SSCP method". BMC Med. Genet. 3: 6. doi:10.1186/1471-2350-3-6. PMC 117798. PMID 12147176.
  • Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519.
  • Fujita Y, Ezura Y, Emi M, et al. (2004). "Hypercholesterolemia associated with splice-junction variation of inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) gene". J. Hum. Genet. 49 (1): 24–8. doi:10.1007/s10038-003-0101-8. PMID 14661079.
  • Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell. Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
  • Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718.
  • Kroczynska B, King-Simmons L, Alloza L, et al. (2006). "BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4". Biochem. Biophys. Res. Commun. 338 (3): 1467–77. doi:10.1016/j.bbrc.2005.10.101. PMID 16271702.
  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.