IL17RD

IL17RD
Identifiers
Aliases	IL17RD, HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D
External IDs	MGI: 2159727 HomoloGene: 9717 GeneCards: IL17RD
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p14.3 Start 57,089,982 bp[1] End 57,170,306 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 27,038,941 bp[2] End 27,107,286 bp[2]
Gene ontology Molecular function • interleukin-17 receptor activity Cellular component • cytoplasm • integral component of membrane • Golgi apparatus • membrane • Golgi membrane • plasma membrane • integral component of plasma membrane • nucleoplasm Biological process • MAPK cascade • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54756	171463
Ensembl	ENSG00000144730	ENSMUSG00000040717
UniProt	Q8NFM7	Q8JZL1
RefSeq (mRNA)	NM_017563 NM_001318864	NM_027265 NM_134437
RefSeq (protein)	NP_001305793 NP_060033	NP_602319
Location (UCSC)	Chr 3: 57.09 – 57.17 Mb	Chr 14: 27.04 – 27.11 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interleukin 17 receptor D is a protein that in humans is encoded by the IL17RD gene. ^[5]

Function

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.