IL17RC

IL17RC
Identifiers
AliasesIL17RC, IL17-RL, IL17RL, CANDF9, interleukin 17 receptor C
External IDsMGI: 2159336 HomoloGene: 15894 GeneCards: IL17RC
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p25.3|3p25.3-p24.1Start9,917,074 bp[1]
End9,933,630 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

84818

171095

Ensembl

ENSG00000163702

ENSMUSG00000030281

UniProt

Q8NAC3

Q8K4C2

RefSeq (mRNA)

NM_134159
NM_178942

RefSeq (protein)

NP_598920
NP_849273

Location (UCSC)Chr 3: 9.92 – 9.93 MbChr 6: 113.47 – 113.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.[5][6]

Function

This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000163702 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030281 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Haudenschild D, Moseley T, Rose L, Reddi AH (February 2002). "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer". The Journal of Biological Chemistry. 277 (6): 4309–16. doi:10.1074/jbc.M109372200. PMID 11706037.
  6. 1 2 "Entrez Gene: IL17RC interleukin 17 receptor C".

Further reading

  • Gerritsen ME, Tomlinson JE, Zlot C, Ziman M, Hwang S (October 2003). "Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells". British Journal of Pharmacology. 140 (4): 595–610. doi:10.1038/sj.bjp.0705494. PMC 1574080. PMID 14504135.
  • Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH (September 2006). "Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA". The Prostate. 66 (12): 1268–74. doi:10.1002/pros.20422. PMID 16688746.
  • Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, Tocker J, Peschon J (July 2006). "Cutting edge: interleukin 17 signals through a heteromeric receptor complex". Journal of Immunology. 177 (1): 36–9. doi:10.4049/jimmunol.177.1.36. PMID 16785495.
  • Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD (October 2007). "Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F". Journal of Immunology. 179 (8): 5462–73. doi:10.4049/jimmunol.179.8.5462. PMC 2849293. PMID 17911633.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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