Hypodermin C

Hypodermin C
Identifiers
EC number 3.4.21.49
CAS number 122191-36-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Hypodermin C (EC 3.4.21.49, Hypoderma collagenase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins including native collagen at -Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment

This enzyme is isolated from the larva of a warble fly, Hypoderma lineatum.

References

  1. Lecroisey, A.; Boulard, C.; Keil, B. (1979). "Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum". Eur. J. Biochem. 101: 385–393. doi:10.1111/j.1432-1033.1979.tb19730.x. PMID 230030.
  2. Lecroisey, A.; Keil, B. (1985). "Specificity of the collagenase from the insect Hypoderma lineatum". Eur. J. Biochem. 152: 123–130. doi:10.1111/j.1432-1033.1985.tb09171.x. PMID 2995028.
  3. Lecroisey, A.; Gilles, A.-M.; De Wolf, A.; Keil, B. (1987). "Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum". J. Biol. Chem. 262: 7546–7551. PMID 3034899.
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