Glucosyl-DNA beta-glucosyltransferase

Glucosyl-DNA beta-glucosyltransferase
Identifiers
EC number 2.4.1.28
CAS number 9030-15-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a glucosyl-DNA beta-glucosyltransferase (EC 2.4.1.28) is an enzyme that catalyzes the chemical reaction in which a beta-D-glucosyl residue is transferred from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA. This enzyme resembles DNA beta-glucosyltransferase in that respect.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase. Other names in common use include T6-glucosyl-HMC-beta-glucosyl transferase, T6-beta-glucosyl transferase, uridine diphosphoglucose-glucosyldeoxyribonucleate, and beta-glucosyltransferase.

References

    • Kornberg SR, Zimmerman SB, Kornberg A (1961). "Glucosylation of deoxyribonucleic acid by enzymes from bacteriophage-infected Escherichia coli". J. Biol. Chem. 236: 1487&ndash, 1493. PMID 13753193.
    • Tomaschewski J, Gram H, Crabb JW, Rüger W (1985). "T4-induced alpha- and beta-glucosyltransferase: cloning of the genes and a comparison of their products based on sequencing data". Nucleic Acids Res. 13: 7551–68. doi:10.1093/nar/13.21.7551. PMC 322070. PMID 2999696.


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