GTF3C4

GTF3C4
Identifiers
AliasesGTF3C4, KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA, TF3C-delta, general transcription factor IIIC subunit 4
External IDsMGI: 2138937 HomoloGene: 8147 GeneCards: GTF3C4
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q34.13Start132,670,035 bp[1]
End132,694,955 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9329

269252

Ensembl

ENSG00000125484

ENSMUSG00000035666

UniProt

Q9UKN8

Q8BMQ2

RefSeq (mRNA)

NM_012204

NM_001166033
NM_172977

RefSeq (protein)

NP_036336

NP_001159505
NP_766565

Location (UCSC)Chr 9: 132.67 – 132.69 MbChr 2: 28.82 – 28.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

General transcription factor 3C polypeptide 4 is a protein that in humans is encoded by the GTF3C4 gene.[5][6]

Interactions

GTF3C4 has been shown to interact with GTF3C2,[5] GTF3C1,[5] POLR3C[5][7] and GTF3C5.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000125484 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035666 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 3 4 5 Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. 19 (11): 7697–704. doi:10.1128/mcb.19.11.7697. PMC 84812. PMID 10523658.
  6. ↑ "Entrez Gene: GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa".
  7. ↑ Hsieh YJ, Wang Z, Kovelman R, Roeder RG (Jul 1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. 19 (7): 4944–52. PMC 84305. PMID 10373544.

Further reading

  • Dumay-Odelot H, Marck C, Durrieu-Gaillard S, Lefebvre O, Jourdain S, Prochazkova M, Pflieger A, Teichmann M (2007). "Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC". J. Biol. Chem. 282 (23): 17179–89. doi:10.1074/jbc.M611542200. PMID 17409385.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Hsieh YJ, Wang Z, Kovelman R, Roeder RG (1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. 19 (7): 4944–52. PMC 84305. PMID 10373544.
  • Jang KL, Collins MK, Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC". J. Acquir. Immune Defic. Syndr. 5 (11): 1142–7. PMID 1403646.


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