GDP-D-glucose phosphorylase

GDP-D-glucose phosphorylase
Identifiers
EC number 2.7.7.78
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

GDP-D-glucose phosphorylase (EC 2.7.7.78) is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

GDP-alpha-D-glucose + phosphate alpha-D-glucose 1-phosphate + GDP

The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates.

References

  1. Adler, L.N.; Gomez, T.A.; Clarke, S.G.; Linster, C.L. (2011). "A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals". J. Biol. Chem. 286: 21511–21523. doi:10.1074/jbc.m111.238774. PMC 3122210. PMID 21507950.
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