Filmfare Award for Best Actress – Tamil

2000s

• 2001 - Laila for Nandha as Kalyani^[51]
  • Devayani - Aanandham as Bharathi
  • Jyothika - Poovellam Un Vasam as Chella

• 2003 - Laila for Pithamagan as Manju ^[52]
  • Jyothika - Dhool as Easwari
  • Jyothika - Kaakha Kaakha as Maya
  • Simran - Kovilpatti Veeralakshmi as Kovilpatti Veeralakshmi
  • Sneha - Parthiban Kanavu as Sathya and Janani

• 2007 – Priyamani for Paruthiveeran as Muththazhagu^[53]
  • Asin Thottumkal – Pokkiri as Shruthi
  • Jyothika – Mozhi as Archana
  • Nayantara – Billa as Sasha
  • Tamannaah – Kalloori as Shobana
  • Archana - Onbadhu Roobai Nottu as Velayi
• 2008 – Parvathy for Poo as Maari
  • Asin Thottumkal — Dasavatharam as Andal/Kothai Radha
  • Genelia D'Souza – Santosh Subramaniam as Hasini
  • Nayantara – Yaaradi Nee Mohini as Keerthi
  • Sneha – Pirivom Santhippom as Visalatchi
  • Swathi – Subramaniyapuram as Thulasi
• 2009 Pooja Umashankar – Naan Kadavul as Hamshavalli
  • Padmapriya Janakiraman – Pokkisham as Nadhira
  • Sriya Reddy – Kanchivaram as Annam
  • Sneha – Achamundu Achamundu as Malini Kumar
  • Tamannaah – Kandein Kadhalai as Anjali

2010s

• 2010 Anjali – Angadi Theru as Sermakkani
  • Amala Paul – Mynaa as Mynaa
  • Nayanthara – Boss Engira Bhaskaran as Chandrika Shanmugasundaram
  • Reema Sen – Aayirathil Oruvan as Anitha Pandiyan
  • Tamannaah – Paiyya as Charulatha
  • Trisha Krishnan – Vinnaithaandi Varuvaayaa as Jessie Thekekuttu
• 2011 Anjali – Engaeyum Eppothum as Manimegalai Ramasamy
  • Asin Thottumkal – Kaavalan as Meera
  • Anushka Shetty – Deiva Thirumagal as Anuradha Ragunathan
  • Iniya – Vaagai Sooda Vaa as Madhi
  • Richa Gangopadhyay – Mayakkam Enna as Yamini
  • Shruti Haasan – 7aum Arivu as Subha
• 2012 Samantha – Neethane En Ponvasantham as Nithya Vasudevan
  • Lakshmi Menon – Kumki as Alli
  • Shruti Haasan – 3 as Janani
  • Amala Paul – Kadhalil Sodhappuvadhu Yeppadi as Parvathi
  • Sunaina – Neerparavai as Esther
• 2013 - Nayanthara - Raja Rani as Regina John
  • Parvathy – Maryan as Panimalar
  • Pooja - Vidiyum Munn as Rekha
  • Sneha – Haridas as Amudhavalli
  • Trisha Krishnan – Endrendrum Punnagai as Priya
  • Vedhicka - Paradesi as Angamma
• 2014 - Malavika Nair - Cuckoo as Sudhanthirakodi
  • Amala Paul - Velaiyilla Pattathari as Shalini
  • Catherine Tresa – Madras as Kalaiarasi
  • Samantha – Kaththi as Ankitha
  • Vedhicka - Kaaviya Thalaivan as Vadivambal
• 2015 - Nayantara – Naanum Rowdy Dhaan as Kadhambari
  • Nithya Menen – OK Kanmani as Tara Kalingarayar
  • Jyothika – 36 Vayadhinile as Vasanthi Tamizhselvan
  • Iyshwarya Rajesh – Kaaka Muttai as mother
  • Gauthami – Papanasam as Rani Suyambulingam
• 2016 -Ritika Singh – Irudhi Suttru as Ezhil Madhi
  • Nayanthara – Iru Mugan as Meera George
  • Trisha Krishnan - Kodi as Rudhra
  • Samantha Ruth Prabhu – 24 as Sathya
  • Samantha Ruth Prabhu – Theri as Mithra Vijaykumar
  • Tamannaah – Devi as Devi
• 2017 -Nayantara – Aramm as Madhivadhani IAS
  • Amala Paul – Thiruttu Payale 2 as Agalya Selvam
  • Aditi Balan – Aruvi as Aruvi
  • Andrea Jeremiah – Taramani as Althea Johnson
  • Jyotika – Magalir Mattum as Prabhavathy
  • Revathi – Power Paandi as Poothendral