Endopeptidase La

Endopeptidase La
Identifiers
EC number 3.4.21.53
CAS number 79818-35-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Endopeptidase La (EC 3.4.21.53, ATP-dependent serine proteinase, lon proteinase, protease La, proteinase La, ATP-dependent lon proteinase, ATP-dependent protease La, Escherichia coli proteinase La, Escherichia coli serine proteinase La, gene lon protease, gene lon proteins, PIM1 protease, PIM1 proteinase, serine protease La) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins in presence of ATP

This enzyme is a product of the lon gene in Escherichia coli.

References

  1. Desautels M, Goldberg AL (October 1982). "Demonstration of an ATP-dependent, vanadate-sensitive endoprotease in the matrix of rat liver mitochondria". The Journal of Biological Chemistry. 257 (19): 11673–9. PMID 6749845.
  2. Larimore FS, Waxman L, Goldberg AL (April 1982). "Studies of the ATP-dependent proteolytic enzyme, protease La, from Escherichia coli". The Journal of Biological Chemistry. 257 (8): 4187–95. PMID 7040380.
  3. Chin DT, Goff SA, Webster T, Smith T, Goldberg AL (August 1988). "Sequence of the lon gene in Escherichia coli. A heat-shock gene which encodes the ATP-dependent protease La". The Journal of Biological Chemistry. 263 (24): 11718–28. PMID 3042779.
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