Deslanoside

Deslanoside
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C01AA07 (WHO) ;
Identifiers
	IUPAC name (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide;
CAS Number	17598-65-1 ;
PubChem CID	28620;
IUPHAR/BPS	6806;
DrugBank	DB01078 ;
ChemSpider	26618 ;
UNII	YGY317RK75;
KEGG	D01240 ;
ChEBI	CHEBI:31468 ;
ChEMBL	CHEMBL1614 ;
ECHA InfoCard	100.037.774
Chemical and physical data
Formula	C47H74O19
Molar mass	943.08 g/mol
	InChI InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 ; Key:OBATZBGFDSVCJD-LALPQLPRSA-N ;
(verify)

Deslanoside (trade name Cedilanide in Brazil^[1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove.^[2]^[3]

References

↑ Drugs.com: Cedilanide
↑ Bakke, O. M.; Aslaksen, A.; Lehmann, V.; Lien, E. (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of cardiovascular pharmacology. 3 (5): 1015–1025. doi:10.1097/00005344-198109000-00012. PMID 6168847.
↑ Budavari, Susan, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123 , 2967

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.