dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase

DTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase
Identifiers
EC number 2.3.1.209
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

DTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase (EC 2.3.1.209, VIOB) is an enzyme with systematic name acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase.[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose

4-acetamido-4,6-dideoxy-alpha-D-glucose is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7.

References

  1. Wang, Y.; Xu, Y.; Perepelov, A.V.; Qi, Y.; Knirel, Y.A.; Wang, L.; Feng, L. (2007). "Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7". J. Bacteriol. 189: 8626–8635. doi:10.1128/jb.00777-07. PMC 2168959. PMID 17905981.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.