D-glycero-alpha-D-manno-heptose-7-phosphate kinase

D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Identifiers
EC number 2.7.1.168
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

D-glycero-alpha-D-manno-heptose-7-phosphate kinase (EC 2.7.1.168, D-alpha-D-heptose-7-phosphate kinase, hdda (gene)) is an enzyme with systematic name ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction

D-glycero-alpha-D-manno-heptose 7-phosphate + ATP D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP

The enzyme participates in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.

References

  1. Kneidinger, B.; Graninger, M.; Puchberger, M.; Kosma, P.; Messner, P. (2001). "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". J. Biol. Chem. 276: 20935–20944. doi:10.1074/jbc.m100378200. PMID 11279237.
  2. Valvano, M.A.; Messner, P.; Kosma, P. (2002). "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology. 148: 1979–1989. doi:10.1099/00221287-148-7-1979. PMID 12101286.
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