Chalcone 4'-O-glucosyltransferase

Chalcone 4'-O-glucosyltransferase
Identifiers
EC number 2.4.1.286
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Chalcone 4'-O-glucosyltransferase (EC 2.4.1.286, 4'CGT) is an enzyme with systematic name UDP-alpha-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucosyltransferase.[1] This enzyme catalyses the following chemical reaction

(1) UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
(2) UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone UDP + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside

This enzyme is isolated from the plant Antirrhinum majus (snapdragon).

References

  1. Ono, E.; Fukuchi-Mizutani, M.; Nakamura, N.; Fukui, Y.; Yonekura-Sakakibara, K.; Yamaguchi, M.; Nakayama, T.; Tanaka, T.; Kusumi, T.; Tanaka, Y. (2006). "Yellow flowers generated by expression of the aurone biosynthetic pathway". Proc. Natl. Acad. Sci. USA. 103 (29): 11075–11080. Bibcode:2006PNAS..10311075O. doi:10.1073/pnas.0604246103. PMC 1544175. PMID 16832053.
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