Beta-apo-4'-carotenal oxygenase

Beta-apo-4'-carotenal oxygenase
Identifiers
EC number 1.2.1.82
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-apo-4'-carotenal oxygenase (EC 1.2.1.82, beta-apo-4'-carotenal dehydrogenase, YLO-1, carD (gene)) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction:

4'-apo-beta,psi-caroten-4'-al + NAD+ + H2O neurosporaxanthin + NADH + 2 H+

Neurosporaxanthin is responsible for the orange color of Neurospora.

References

  1. Estrada, A.F.; Youssar, L.; Scherzinger, D.; Al-Babili, S.; Avalos, J. (2008). "The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway". Mol. Microbiol. 69 (5): 1207–1220. doi:10.1111/j.1365-2958.2008.06349.x. PMID 18627463.
  2. Diaz-Sanchez, V.; Estrada, A.F.; Trautmann, D.; Al-Babili, S.; Avalos, J. (2011). "The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi". FEBS J. 278 (17): 3164–3176. doi:10.1111/j.1742-4658.2011.08242.x. PMID 21749649.
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