Baccharis oxide synthase

Baccharis oxide synthase
Identifiers
EC number 5.4.99.51
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Baccharis oxide synthase (EC 5.4.99.51) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baccharis-oxide-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene baccharis oxide

The enzyme from Stevia rebaudiana also gives traces of other triterpenoids.

References

  1. Shibuya, M.; Sagara, A.; Saitoh, A.; Kushiro, T.; Ebizuka, Y. (2008). "Biosynthesis of baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring". Org. Lett. 10: 5071–5074. doi:10.1021/ol802072y. PMID 18850716.
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