Arsenate-mycothiol transferase

Arsenate-mycothiol transferase
Identifiers
EC number 2.8.4.2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Arsenate-mycothiol transferase (EC 2.8.4.2, ArsC1, ArsC2, mycothiol:arsenate transferase) is an enzyme with systematic name mycothiol:arsenate S-arsenotransferase.[1] This enzyme catalyses the following chemical reaction

mycothiol + arsenate arseno-mycothiol + H2O

Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate.

References

  1. Ordonez, E.; Van Belle, K.; Roos, G.; De Galan, S.; Letek, M.; Gil, J.A.; Wyns, L.; Mateos, L.M.; Messens, J. (2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". J. Biol. Chem. 284: 15107–15116. doi:10.1074/jbc.m900877200. PMC 2685692. PMID 19286650.
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