Amyloid cardiomyopathy

Amyloid cardiomyopathy

Amyloid cardiomyopathy (stiff heart syndrome)[1] is associated with the systemic production and release of many amyloidogenic proteins, especially immunoglobulin light chain or transthyretin (TTR).[2] It can be characterized by the extracellular deposition of amyloid in the heart.[3] Amyloids are foldable proteins that all stick together to build fibrils.[4]

References

  1. ↑ "Cardiac amyloidosis: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2017-12-01.
  2. ↑ Liao, Ronglih; Ward, Jennifer E. (2017-06-09). "Amyloid Cardiomyopathy: Disease on the Rise". Circulation Research. 120 (12): 1865–1867. doi:10.1161/CIRCRESAHA.117.310643. ISSN 0009-7330. PMC 5584551. PMID 28596171.
  3. ↑ Falk, Rodney H.; Dubrey, Simon W. (2010-01-01). "Amyloid Heart Disease". Progress in Cardiovascular Diseases. Unusual Cardiomyopathies. 52 (4): 347–361. doi:10.1016/j.pcad.2009.11.007.
  4. ↑ "Amyloid". Wikipedia. 2017-11-26.


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