3-Epi-6-deoxocathasterone 23-monooxygenase

3-Epi-6-deoxocathasterone 23-monooxygenase
Identifiers
EC number 1.14.13.112
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-Epi-6-deoxocathasterone 23-monooxygenase (EC 1.14.13.112, cytochrome P450 90C1, CYP90D1, CYP90C1) is an enzyme with systematic name 3-epi-6-deoxocathasterone,NADPH:oxygen oxidoreductase (C-23-hydroxylating).[1] This enzyme catalyses the following chemical reaction

(1) 3-epi-6-deoxocathasterone + NADPH + H+ + O2 6-deoxotyphasterol + NADP+ + H2O
(2) (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADPH + H+ + O2 3-dehydro-6-deoxoteasterone + NADP+ + H2O

3-Epi-6-deoxocathasterone 23-monooxygenase takes part in brassinosteroid biosynthesis.

References

  1. Ohnishi T, Szatmari AM, Watanabe B, Fujita S, Bancos S, Koncz C, Lafos M, Shibata K, Yokota T, Sakata K, Szekeres M, Mizutani M (November 2006). "C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis". The Plant Cell. 18 (11): 3275–88. doi:10.1105/tpc.106.045443. PMC 1693957. PMID 17138693.
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